| Pharmacy (English) | |||||
| Bachelor | TR-NQF-HE: Level 6 | QF-EHEA: First Cycle | EQF-LLL: Level 6 | ||
| Course Code: | PHA423 | ||||
| Course Name: | Pharmaceutical Techology IV | ||||
| Course Semester: | Spring | ||||
| Course Credits: |
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| Language of instruction: | EN | ||||
| Course Requirement: | |||||
| Does the Course Require Work Experience?: | No | ||||
| Type of course: | Necessary | ||||
| Course Level: |
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| Mode of Delivery: | Face to face | ||||
| Course Coordinator : | Ar.Gör. SULTAN DİCLE YERLİKAYA | ||||
| Course Lecturer(s): | Ass. Prof. Samet Özdemir | ||||
| Course Assistants: |
| Course Objectives: | The aim of this course is to teach students biopharmaceutics and pharmacokinetics, to introduce modern therapeutic and theranostic systems and to teach drug targeting. |
| Course Content: | In this course, students learn basic pharmacokinetic parameters, gain knowledge about kinetic rate processes, have an idea about compartment models used in pharmacokinetics, learn modern pharmaceutical systems, theranostics and drug targeting. |
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The students who have succeeded in this course;
1) To be able to access, evaluate and apply current scientific knowledge in the field of pharmacy 2) To be able to convey information to patients, health personnel and society on all issues related to medicines 3) To be able to have advanced knowledge about therapeutic effects of active pharmaceutical ingredients, drug forms, pharmacokinetic properties and stability 4) Recognise the quality assurance issues and processes of all pharmaceutical products, control and standardisation 5) To be able to use the knowledge and equipment related to the administration and use of the drug to the patient, to provide rational and safe drug use 6) To be able to have knowledge about the production of natural and synthetic drug raw materials and production technologies 7) To be able to take part in the development and production of pharmaceutical biotechnology and new generation pharmaceutical products 8) To be able to have knowledge about public health, environmental protection and occupational safety 9) Should be able to take part in pharmacy services in the hospital at every stage and ensure the safety of the patient's medication 10) To be able to have knowledge about licensing conditions, data protection, patent issues in pharmaceuticals 11) To be able to gain administrative and technical equipment in every field where the pharmacy profession gives responsibility with the law, to be able to produce solutions to problems in line with scientific data / evidence |
| Week | Subject | Related Preparation |
| 1) | Biopharmaceutical phase Drug absorption, distribution, metabolism and elimination, ADME | |
| 2) | Effect of routes of administration on absorption and bioavailability Factors affecting bioavailability Absolute and relative bioavailability calculations | |
| 3) | The concept of bioequivalence Bioequivalence studies and related guidelines | |
| 4) | Bioequivalence and equivalence types in drugs Bioavailability and bioequivalence, clinical study protocols | |
| 5) | Biopharmaceutical classification system, solubility and dissolution rate parameters Introduction to pharmacokinetics | |
| 6) | IV applications and examination of pharmacokinetic parameters Oral administration and examination of pharmacokinetic parameters | |
| 7) | Pharmacokinetic behavior of active substances in the body Compartment models Pharmacokinetic modeling | |
| 8) | Midterm | |
| 9) | Clinical study examples and evaluations | |
| 10) | Radiopharmaceuticals | |
| 11) | Pediatric and geriatric medicines Dyes and flavour modifiers | |
| 12) | Enzyme preparations Hormones and other preparations | |
| 13) | Packaging of medicines | |
| 14) | Case study | |
| 15) | Case study | |
| 16) | Final exam |
| Course Notes / Textbooks: | 1. Farmasötik Teknoloji, Temel konular ve dozaj şekilleri, A. Z. Gürsoy, Kontrollü Salım Sistemleri Derneği, 2012 2. Ansel's Pharmaceutical Dosage Forms and Drug Delivery Systems, Allen, L. V., & McPherson, T. B., Wolters Kluwer Health, 2021. 3. Aulton's Pharmaceutics: The Design and Manufacture of Medicines, Taylor, K., & Aulton, M. E. Elsevier, 2021. 4. Applied Biopharmaceutics & Pharmacokinetics, Shargel, L., & Yu, A. B. C., Mc Graw Hill, 2016. 5. Farmakokinetik, Gladtke, E. & Von Hattingberg, H. M. Springer, 1973. |
| References: | 1. Farmasötik Teknoloji, Temel konular ve dozaj şekilleri, A. Z. Gürsoy, Kontrollü Salım Sistemleri Derneği, 2012 2. Ansel's Pharmaceutical Dosage Forms and Drug Delivery Systems, Allen, L. V., & McPherson, T. B., Wolters Kluwer Health, 2021. 3. Aulton's Pharmaceutics: The Design and Manufacture of Medicines, Taylor, K., & Aulton, M. E. Elsevier, 2021. 4. Applied Biopharmaceutics & Pharmacokinetics, Shargel, L., & Yu, A. B. C., Mc Graw Hill, 2016. 5. Farmakokinetik, Gladtke, E. & Von Hattingberg, H. M. Springer, 1973. |
| No Effect | 1 Lowest | 2 Medium | 3 Highest |
| Program Outcomes | Level of Contribution |
| Alan Çalışması | |
| Akran Değerlendirmesi | |
| Anlatım | |
| Beyin fırtınası /Altı şapka | |
| Bireysel çalışma ve ödevi | |
| Course | |
| Okuma | |
| Homework | |
| Sosyal Faaliyet | |
| Teknik gezi | |
| Örnek olay çalışması | |
| Web Tabanlı Öğrenme |
| Yazılı Sınav (Açık uçlu sorular, çoktan seçmeli, doğru yanlış, eşleştirme, boşluk doldurma, sıralama) | |
| Homework | |
| Gözlem | |
| Sunum | |
| Raporlama | |
| Bilgisayar Destekli Sunum | |
| Örnek olay sunma |
| Semester Requirements | Number of Activities | Level of Contribution |
| Midterms | 1 | % 40 |
| Final | 1 | % 60 |
| total | % 100 | |
| PERCENTAGE OF SEMESTER WORK | % 40 | |
| PERCENTAGE OF FINAL WORK | % 60 | |
| total | % 100 | |
| Activities | Number of Activities | Aktiviteye Hazırlık | Aktivitede Harçanan Süre | Aktivite Gereksinimi İçin Süre | Workload | ||
| Course Hours | 14 | 2 | 28 | ||||
| Study Hours Out of Class | 14 | 4 | 56 | ||||
| Homework Assignments | 7 | 4 | 28 | ||||
| Quizzes | 3 | 1 | 3 | ||||
| Midterms | 1 | 2 | 2 | ||||
| Final | 1 | 2 | 2 | ||||
| Total Workload | 119 | ||||||