Pharmacy (English)
Bachelor TR-NQF-HE: Level 6 QF-EHEA: First Cycle EQF-LLL: Level 6

Course General Introduction Information

Course Code: PHA324
Course Name: Pharmaceutical Chemistry Laboratory-II
Course Semester: Spring
Course Credits:
ECTS
2
Language of instruction: EN
Course Requirement:
Does the Course Require Work Experience?: No
Type of course: Necessary
Course Level:
Bachelor TR-NQF-HE:6. Master`s Degree QF-EHEA:First Cycle EQF-LLL:6. Master`s Degree
Mode of Delivery: Face to face
Course Coordinator : Ar.Gör. TUĞÇE CİNEK
Course Lecturer(s): Prof. Dr. Şeref Demirayak, Prof. Dr. İlkay Küçükgüzel
Course Assistants:

Course Purpose and Content

Course Objectives: The objective of this course is to teach the students the basics and application of the quantitative analysis techniques on active pharmaceutical ingredients using titration, UV-Vis spectrophotometry and high pressure liquid chromatography methods.
Course Content: This course includes provide basic information on the quantitative analysis of pharmaceutical active ingredients in pharmaceutical formulations by titration, UV-Vis spectroscopy, and high pressure liquid chromatography.

Learning Outcomes

The students who have succeeded in this course;
1) Access, evaluate and apply up-to-date scientific knowledge in the field of pharmacy
2) It conveys information to patients, health personnel and society on all matters related to drugs.
3) Has the necessary knowledge about the therapeutic effects, drug forms, pharmacokinetic properties, stability and incompatibilities of drug active substances and can use this information.
4) Recognizes, controls and standardizes quality assurance issues and processes of all pharmaceutical-related products.
5) Has knowledge and equipment about the administration and use of the drug to the patient, advises on rational and safe drug use, and supports pharmacovigilance practices.
6) Has knowledge about the production and production technologies of natural and synthetic pharmaceutical raw materials.
7) Have knowledge about the concepts related to the functioning, maintenance and pathology of biological systems that form the basis of human health.
8) Has sufficient knowledge and application skills on research, development and production of pharmaceutical and cosmetic products.
9) Plans and implements all subjects within the scope of pharmacy services in the hospital.
10) Has knowledge about licensing conditions, data protection, patent and pharmacoeconomics in pharmaceuticals.
11) She/He is administratively and technically equipped in every field where the pharmacy profession is responsible by law, and produces solutions to problems in line with scientific data / evidence.
12) Combines basic and applied sciences with pharmacy profession practices and uses them in the field of pharmacy.
13) Has sufficient knowledge and application skills on physical, chemical, biological and toxicological analyzes of pharmaceutical, biotechnological and radiopharmaceutical products.
14) Acts in accordance with ethical and legal principles in the field of pharmacy.
15) Has the necessary competencies to work with colleagues and other health professionals in terms of communicative, managerial and social skills.
16) Provides consultancy on medicinal plants, herbal supplements and food supplements.
17) Knows pharmaceutical care practices, understands and evaluates drug interactions.
18) Knows the risks associated with the use of drugs and other chemical substances and laboratory practice.

Course Flow Plan

Week Subject Related Preparation
1) Theoretical basis of laboratory studies
2) Theoretical basis of laboratory studies
3) Principles of safety rules in laboratory
4) Principals of UV spectrophotometric determination
5) Alkalimetric aspirin determination
6) Fundamentals of high-pressure liquid chromatography
7) Quantitative analysis using high-pressure liquid chromatography
8) Midterm exam
9) Quantitative analysis of Vitamin E in tablets and capsules
10) Derivatization methods in quantitative analysis
11) Quantitative analysis with spectrophotometric methods in visible range
12) Determination of Vitamin B6 by UV spectrophotometry
13) Determination of paracetamol in formulations by UV spectrophotometry
14) Assessment of experimental results in MS Excel software.
15) Compensation laboratory

Sources

Course Notes / Textbooks: İlaçların Tanınması ve Kantitatif Tayini. Nedime Ergenç, Aysel Gürsoy,Öznur Ateş (1999).İstanbul Üniversitesi Yayınları


1.Quantitative Analysis of Drugs in Pharmaceutical Formulations. P.D. Sethi .(2015)CBS Publishers
2. Pharmaceutical Drug Analysis. A.Kar. (2008) New Age International Publishers
References: İlaçların Tanınması ve Kantitatif Tayini. Nedime Ergenç, Aysel Gürsoy,Öznur Ateş (1999).İstanbul Üniversitesi Yayınları


1.Quantitative Analysis of Drugs in Pharmaceutical Formulations. P.D. Sethi .(2015)CBS Publishers
2. Pharmaceutical Drug Analysis. A.Kar. (2008) New Age International Publishers

Course - Learning Outcome Relationship

No Effect 1 Lowest 2 Medium 3 Highest
       
Program Outcomes Level of Contribution

Learning Activity and Teaching Methods

Anlatım
Course
Labs
Rapor Yazma
Soru cevap/ Tartışma
Uygulama (Modelleme, Tasarım, Maket, Simülasyon, Deney vs.)

Measurement and Evaluation Methods and Criteria

Yazılı Sınav (Açık uçlu sorular, çoktan seçmeli, doğru yanlış, eşleştirme, boşluk doldurma, sıralama)
Raporlama

Assessment & Grading

Semester Requirements Number of Activities Level of Contribution
Midterms 1 % 40
Final 1 % 60
total % 100
PERCENTAGE OF SEMESTER WORK % 40
PERCENTAGE OF FINAL WORK % 60
total % 100

İş Yükü ve AKTS Kredisi Hesaplaması

Activities Number of Activities Aktiviteye Hazırlık Aktivitede Harçanan Süre Aktivite Gereksinimi İçin Süre Workload
Laboratory 14 3 42
Study Hours Out of Class 14 3 42
Quizzes 6 1 6
Midterms 1 1 1
Final 1 1 1
Total Workload 92