Istanbul Health and Technology University INFORMATION PACKAGE / COURSE CATALOGUE
| Pharmacy | |||||
| Bachelor | TR-NQF-HE: Level 6 | QF-EHEA: First Cycle | EQF-LLL: Level 6 | ||
Course General Introduction Information
| Course Code: | ECZ423 | ||||
| Course Name: | Pharmaceutical Technology IV | ||||
| Course Semester: | Spring | ||||
| Course Credits: |
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| Language of instruction: | TR | ||||
| Course Requirement: | |||||
| Does the Course Require Work Experience?: | No | ||||
| Type of course: | Necessary | ||||
| Course Level: |
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| Mode of Delivery: | |||||
| Course Coordinator : | Ar.Gör. SULTAN DİCLE YERLİKAYA | ||||
| Course Lecturer(s): | Prof. Mine Özyazıcı | ||||
| Course Assistants: |
Course Purpose and Content
| Course Objectives: | The aim of this course is to teach students biopharmaceutics and pharmacokinetics, to introduce modern therapeutic and theranostic systems and to teach drug targeting. |
| Course Content: | Pharmaceutical Technology-IV course, basic pharmacokinetics, biopharmaceutics, in vitro in vivo correlation, new/modern drug delivery systems, nanotechnological preparations, medical materials, pharmaceuticals It includes topics such as the basic processes related to licensing. |
Learning Outcomes
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The students who have succeeded in this course;
1) To be able to access, evaluate and apply current scientific knowledge in the field of pharmacy 2) To be able to convey information to patients, health personnel and society on all issues related to medicines 3) To be able to have advanced knowledge about therapeutic effects of active pharmaceutical ingredients, drug forms, pharmacokinetic properties and stability 4) Recognise the quality assurance issues and processes of all pharmaceutical products, control and standardisation 5) To be able to use the knowledge and equipment related to the administration and use of the drug to the patient, to provide rational and safe drug use 6) To be able to have knowledge about the production of natural and synthetic drug raw materials and production technologies 7) To be able to take part in the development and production of pharmaceutical biotechnology and new generation pharmaceutical products 8) Halk sağlığı, çevre koruma ve iş güvenliği konularında bilgi sahibi olabilmeli 9) Should be able to take part in pharmacy services in the hospital at every stage and ensure the safety of the patient's medication 10) To be able to have knowledge about licensing conditions, data protection, patent issues in pharmaceuticals 11) To be able to gain administrative and technical equipment in every field where the pharmacy profession gives responsibility with the law, to be able to produce solutions to problems in line with scientific data / evidence 12) To be able to use computer programmes and advanced technologies related to the field of pharmacy 13) To be able to follow and evaluate national and international developments in the field of pharmacy profession |
Course Flow Plan
| Week | Subject | Related Preparation |
| 1) | Biopharmaceutical phase Drug absorption, distribution, metabolism and elimination, ADME | |
| 2) | Effect of routes of administration on absorption and bioavailability Factors affecting bioavailability Absolute and relative bioavailability calculations | |
| 3) | The concept of bioequivalence Bioequivalence studies and related guidelines | |
| 4) | Bioequivalence and equivalence types in drugs Bioavailability and bioequivalence, clinical study protocols | |
| 5) | Biopharmaceutical classification system, solubility and dissolution rate parameters Introduction to pharmacokinetics | |
| 6) | IV applications and examination of pharmacokinetic parameters Oral administration and examination of pharmacokinetic parameters | |
| 7) | Pharmacokinetic behavior of active substances in the body Compartment models Pharmacokinetic modeling | |
| 8) | Midterm | |
| 9) | Clinical study examples and evaluations | |
| 10) | Radiopharmaceuticals | |
| 11) | Pediatric and geriatric medicines Dyes and flavour modifiers | |
| 12) | Enzyme preparations Hormones and other preparations | |
| 13) | Packaging of medicines | |
| 14) | Case study | |
| 15) | Case study | |
| 16) | Final exam |
Sources
| Course Notes / Textbooks: | 1. Farmasötik Teknoloji, Temel konular ve dozaj şekilleri, A. Z. Gürsoy, Kontrollü Salım Sistemleri Derneği, 2012 2. Ansel's Pharmaceutical Dosage Forms and Drug Delivery Systems, Allen, L. V., & McPherson, T. B., Wolters Kluwer Health, 2021. 3. Aulton's Pharmaceutics: The Design and Manufacture of Medicines, Taylor, K., & Aulton, M. E. Elsevier, 2021. 4. Applied Biopharmaceutics & Pharmacokinetics, Shargel, L., & Yu, A. B. C., Mc Graw Hill, 2016. 5. Farmakokinetik, Gladtke, E. & Von Hattingberg, H. M. Springer, 1973. |
| References: | 1. Farmasötik Teknoloji, Temel konular ve dozaj şekilleri, A. Z. Gürsoy, Kontrollü Salım Sistemleri Derneği, 2012 2. Ansel's Pharmaceutical Dosage Forms and Drug Delivery Systems, Allen, L. V., & McPherson, T. B., Wolters Kluwer Health, 2021. 3. Aulton's Pharmaceutics: The Design and Manufacture of Medicines, Taylor, K., & Aulton, M. E. Elsevier, 2021. 4. Applied Biopharmaceutics & Pharmacokinetics, Shargel, L., & Yu, A. B. C., Mc Graw Hill, 2016. 5. Farmakokinetik, Gladtke, E. & Von Hattingberg, H. M. Springer, 1973. |
Course - Learning Outcome Relationship
| No Effect | 1 Lowest | 2 Medium | 3 Highest |
| Program Outcomes | Level of Contribution | |
| 1) | Access, evaluate and apply up-to-date scientific knowledge in the field of pharmacy | 1 |
| 2) | It conveys information to patients, health personnel and society on all matters related to drugs. | 3 |
| 3) | Has the necessary knowledge about the therapeutic effects, drug forms, pharmacokinetic properties, stability and incompatibilities of drug active substances and can use this information. | 3 |
| 4) | Recognizes, controls and standardizes quality assurance issues and processes of all pharmaceutical-related products. | 3 |
| 5) | Has knowledge and equipment about the administration and use of the drug to the patient, advises on rational and safe drug use, and supports pharmacovigilance practices. | 2 |
| 6) | Has knowledge about the production and production technologies of natural and synthetic pharmaceutical raw materials. | 3 |
| 7) | Have knowledge about the concepts related to the functioning, maintenance and pathology of biological systems that form the basis of human health. | 2 |
| 8) | Has sufficient knowledge and application skills on research, development and production of pharmaceutical and cosmetic products. | 1 |
| 9) | Plans and implements all subjects within the scope of pharmacy services in the hospital. | 3 |
| 10) | Has knowledge about licensing conditions, data protection, patent and pharmacoeconomics in pharmaceuticals. | 2 |
| 11) | She/He is administratively and technically equipped in every field where the pharmacy profession is responsible by law, and produces solutions to problems in line with scientific data / evidence. | 2 |
| 12) | Combines basic and applied sciences with pharmacy profession practices and uses them in the field of pharmacy. | 2 |
| 13) | Has sufficient knowledge and application skills on physical, chemical, biological and toxicological analyzes of pharmaceutical, biotechnological and radiopharmaceutical products. | 2 |
| 14) | Acts in accordance with ethical and legal principles in the field of pharmacy. | 1 |
| 15) | Has the necessary competencies to work with colleagues and other health professionals in terms of communicative, managerial and social skills. | 3 |
| 16) | Provides consultancy on medicinal plants, herbal supplements and food supplements. | 2 |
| 17) | Knows pharmaceutical care practices, understands and evaluates drug interactions. | 3 |
| 18) | Knows the risks associated with the use of drugs and other chemical substances and laboratory practice. | 3 |
Learning Activity and Teaching Methods
| Alan Çalışması | |
| Akran Değerlendirmesi | |
| Anlatım | |
| Beyin fırtınası /Altı şapka | |
| Bireysel çalışma ve ödevi | |
| Course | |
| Grup çalışması ve ödevi | |
| Labs | |
| Okuma | |
| Homework | |
| Problem Çözme | |
| Proje Hazırlama | |
| Rapor Yazma | |
| Rol oynama | |
| Seminar | |
| Soru cevap/ Tartışma | |
| Sosyal Faaliyet | |
| Teknik gezi | |
| Tez Hazırlama | |
| Uygulama (Modelleme, Tasarım, Maket, Simülasyon, Deney vs.) | |
| Örnek olay çalışması | |
| Web Tabanlı Öğrenme | |
| Staj/Yerinde Uygulama |
Measurement and Evaluation Methods and Criteria
| Yazılı Sınav (Açık uçlu sorular, çoktan seçmeli, doğru yanlış, eşleştirme, boşluk doldurma, sıralama) | |
| Sözlü sınav | |
| Homework | |
| Uygulama | |
| Gözlem | |
| Bireysel Proje | |
| Grup Projesi | |
| Sunum | |
| Raporlama | |
| Akran Değerlendirmesi | |
| Bilgisayar Destekli Sunum | |
| Tez Sunma | |
| Uzman / Jüri Değerlendirmesi | |
| Örnek olay sunma | |
| Staj/ Yerinde Uygulama Değerlendirmesi | |
| Yarışma |
Assessment & Grading
| Semester Requirements | Number of Activities | Level of Contribution |
| Midterms | 1 | % 40 |
| Final | 1 | % 60 |
| total | % 100 | |
| PERCENTAGE OF SEMESTER WORK | % 40 | |
| PERCENTAGE OF FINAL WORK | % 60 | |
| total | % 100 | |
İş Yükü ve AKTS Kredisi Hesaplaması
| Activities | Number of Activities | Aktiviteye Hazırlık | Aktivitede Harçanan Süre | Aktivite Gereksinimi İçin Süre | Workload | ||
| Course Hours | 14 | 2 | 28 | ||||
| Application | 14 | 2 | 28 | ||||
| Homework Assignments | 14 | 1 | 14 | ||||
| Quizzes | 14 | 1 | 14 | ||||
| Midterms | 1 | 1 | 1 | ||||
| Final | 1 | 1 | 1 | ||||
| Total Workload | 86 | ||||||