Istanbul Health and Technology University INFORMATION PACKAGE / COURSE CATALOGUE
| Pharmacy (English) | |||||
| Bachelor | TR-NQF-HE: Level 6 | QF-EHEA: First Cycle | EQF-LLL: Level 6 | ||
Course General Introduction Information
| Course Code: | PHA323 | ||||
| Course Name: | Pharmaceutical Chemistry-II | ||||
| Course Semester: | Spring | ||||
| Course Credits: |
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| Language of instruction: | EN | ||||
| Course Requirement: | |||||
| Does the Course Require Work Experience?: | No | ||||
| Type of course: | Necessary | ||||
| Course Level: |
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| Mode of Delivery: | Face to face | ||||
| Course Coordinator : | Ar.Gör. TUĞÇE CİNEK | ||||
| Course Lecturer(s): | Prof. Dr. Şeref Demirayak, Prof. Dr. İlkay Küçükgüzel | ||||
| Course Assistants: |
Course Purpose and Content
| Course Objectives: | Pharmaceutical chemistry aims the development of more effective drug molecules by evaluating the drug-biological system chemical relationship. The objective of this course is to teach the chemical structure of drugs, synthesis methods, analysis, action mechanisms, structure-activity relationship and metabolism reactions. |
| Course Content: | The aim of this course is to give a basic concept on the mode of action, structure-activity relationship, synthesis and biotransformation of adrenergic drugs, cholinergic drugs, cardiovascular agents, drugs acting on renin-angiotensin system, diuretic drugs, antiparkinson drugs, and antihyperlipidemic drugs. |
Learning Outcomes
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The students who have succeeded in this course;
1) Access, evaluate and apply up-to-date scientific knowledge in the field of pharmacy 2) It conveys information to patients, health personnel and society on all matters related to drugs. 3) Has the necessary knowledge about the therapeutic effects, drug forms, pharmacokinetic properties, stability and incompatibilities of drug active substances and can use this information. 4) Recognizes, controls and standardizes quality assurance issues and processes of all pharmaceutical-related products. 5) Has knowledge and equipment about the administration and use of the drug to the patient, advises on rational and safe drug use, and supports pharmacovigilance practices. 6) Has knowledge about the production and production technologies of natural and synthetic pharmaceutical raw materials. 7) Have knowledge about the concepts related to the functioning, maintenance and pathology of biological systems that form the basis of human health. 8) Has sufficient knowledge and application skills on research, development and production of pharmaceutical and cosmetic products. 9) Plans and implements all subjects within the scope of pharmacy services in the hospital. 10) Has knowledge about licensing conditions, data protection, patent and pharmacoeconomics in pharmaceuticals. 11) She/He is administratively and technically equipped in every field where the pharmacy profession is responsible by law, and produces solutions to problems in line with scientific data/evidence. 12) Combines basic and applied sciences with pharmacy profession practices and uses them in the field of pharmacy. 13) Has sufficient knowledge and application skills on physical, chemical, biological and toxicological analyzes of pharmaceutical, biotechnological and radiopharmaceutical products. 14) Acts in accordance with ethical and legal principles in the field of pharmacy. 15) Has the necessary competencies to work with colleagues and other health professionals in terms of communicative, managerial and social skills. 16) Provides consultancy on medicinal plants, herbal supplements and food supplements. 17) Knows pharmaceutical care practices, understands and evaluates drug interactions. 18) Knows the risks associated with the use of drugs and other chemical substances and laboratory practice. |
Course Flow Plan
| Week | Subject | Related Preparation |
| 1) | Cholinergic drugs | |
| 2) | Anticholinergic drugs | |
| 3) | Adrenergic drugs | |
| 4) | Adrenergic blocking drugs | |
| 5) | Cardiovascular systemic drugs | |
| 6) | Calcium channel blockers | |
| 7) | ACE inhibitors | |
| 8) | Midterm exam | |
| 9) | AT receptor blockers | |
| 10) | Antihyperlipidemic drugs | |
| 11) | Diuretics | |
| 12) | Steroids | |
| 13) | Mineralocorticoids | |
| 14) | Antiparkinson drugs | |
| 15) | Myorelaxant drugs |
Sources
| Course Notes / Textbooks: | 1. Farmasötik ve Medisinal Kimya (I-II) Hülya Akgün/Ayla Balkan/A. Altan Bilgin/Ünsal Çalış/Sevim Dalkara/Dilek Demir Erol/Hakkı Erdoğan/Mevlüt Ertan/Nesrin Gökhan Kelekçi/Fügen Özkanlı/Erhan Palaska/Selma Saraç/Cihat Şafak/Rahime Şimşek/Birsen Tozkoparan (2019) Hacettepe Üniversitesi Yayınları 2. An Introduction to Medicinal Chemistry, G.L.Patrick, 6. Baskı (2017) Oxford University Press. 3. Foye's Principles of Medicinal Chemistry Victoria F. Roche ,S. William Zito Thomas Lemke, David A. Williams (2019) Walters Kluwer |
| References: |
Course - Learning Outcome Relationship
| No Effect | 1 Lowest | 2 Medium | 3 Highest |
| Program Outcomes | Level of Contribution |
Learning Activity and Teaching Methods
| Anlatım | |
| Course | |
| Soru cevap/ Tartışma |
Measurement and Evaluation Methods and Criteria
| Yazılı Sınav (Açık uçlu sorular, çoktan seçmeli, doğru yanlış, eşleştirme, boşluk doldurma, sıralama) | |
| Homework |
Assessment & Grading
| Semester Requirements | Number of Activities | Level of Contribution |
| Midterms | 1 | % 40 |
| Final | 1 | % 60 |
| total | % 100 | |
| PERCENTAGE OF SEMESTER WORK | % 40 | |
| PERCENTAGE OF FINAL WORK | % 60 | |
| total | % 100 | |
İş Yükü ve AKTS Kredisi Hesaplaması
| Activities | Number of Activities | Aktiviteye Hazırlık | Aktivitede Harçanan Süre | Aktivite Gereksinimi İçin Süre | Workload | ||
| Course Hours | 14 | 3 | 42 | ||||
| Study Hours Out of Class | 14 | 5 | 70 | ||||
| Presentations / Seminar | 1 | 1 | 1 | ||||
| Homework Assignments | 1 | 2 | 2 | ||||
| Quizzes | 1 | 1 | 1 | ||||
| Midterms | 1 | 1 | 1 | ||||
| Final | 1 | 1 | 1 | ||||
| Total Workload | 118 | ||||||