Istanbul Health and Technology University INFORMATION PACKAGE / COURSE CATALOGUE
| Pharmacy (English) | |||||
| Bachelor | TR-NQF-HE: Level 6 | QF-EHEA: First Cycle | EQF-LLL: Level 6 | ||
Course General Introduction Information
| Course Code: | PHA421 | ||||
| Course Name: | Pharmaceutical Chemistry-IV | ||||
| Course Semester: | Spring | ||||
| Course Credits: |
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| Language of instruction: | EN | ||||
| Course Requirement: | |||||
| Does the Course Require Work Experience?: | No | ||||
| Type of course: | Necessary | ||||
| Course Level: |
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| Mode of Delivery: | Face to face | ||||
| Course Coordinator : | Ar.Gör. GÖZDE ÇINAR | ||||
| Course Lecturer(s): | |||||
| Course Assistants: |
Course Purpose and Content
| Course Objectives: | Objective of this course is to teach the importance of chemical structure, synthesis methods, analysis, action mechanisms, structure-activity relationship and metabolism reactions of chemotherapeutics on the development of new chemotherapeutic drugs and new therapeutic approaches. |
| Course Content: | Pharmaceutical Chemistry IV course aims to provide information about the chemical structures, syntheses, structure-activity relationships, mechanisms of action at the receptor level, and metabolic reactions of chemotherapeutic drugs. In this context, antibacterial drugs; antimycobacterial drugs; antifungal drugs ;antiviral drugs; antiprotozoal drugs; anticancer drugs; antiseptics and disinfectants; vitamins will be examined. |
Learning Outcomes
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The students who have succeeded in this course;
1) To be able to interpret the basic principles of chemotherapy 2) Should be able to classify the antibacterial ,antifungal drugs and explain their mechanism of action. 3) Should be able to interpret the chemical mechanism of cancer formation 4) To be able to interpret the mechanism of action of antineoplastic compounds 5) To be able to interpret the mechanism of action of antiviral drugs 6) Should know the structures, synthesis methods, structure-activity relationships, biotransformations of chemotherapeutic drugs |
Course Flow Plan
| Week | Subject | Related Preparation |
| 1) | Antibacterial drugs, sulphonamides | |
| 2) | Antimycobacterial drugs | |
| 3) | Beta-lactam antibiotics | |
| 4) | Beta-lactamase inhibitors, broad spectrum penicillin | |
| 5) | Cephalosporins | |
| 6) | Carbapenems, monobactams | |
| 7) | Macrolids | |
| 8) | Midterm exam | |
| 9) | Bacterial protein synthesis inhibitors | |
| 10) | DNA gyrase inhibitors | |
| 11) | Antifungal drugs | |
| 12) | Antiviral drugs | |
| 13) | Anticancer drugs | |
| 14) | Antiseptic and disinfectants | |
| 15) | Thyroid drugs |
Sources
| Course Notes / Textbooks: | |
| References: | 1. Foye's Principles of Medicinal Chemistry, Victoria F. Roche, S. William Zito Thomas Lemke, David A. Williams 2. An Introduction to Medicinal Chemistry, G.L.Patrick |
Course - Learning Outcome Relationship
| No Effect | 1 Lowest | 2 Medium | 3 Highest |
| Program Outcomes | Level of Contribution |
Learning Activity and Teaching Methods
Measurement and Evaluation Methods and Criteria
Assessment & Grading
| Semester Requirements | Number of Activities | Level of Contribution |
| Midterms | 1 | % 40 |
| Final | 1 | % 60 |
| total | % 100 | |
| PERCENTAGE OF SEMESTER WORK | % 40 | |
| PERCENTAGE OF FINAL WORK | % 60 | |
| total | % 100 | |
İş Yükü ve AKTS Kredisi Hesaplaması
| Activities | Number of Activities | Aktiviteye Hazırlık | Aktivitede Harçanan Süre | Aktivite Gereksinimi İçin Süre | Workload | ||
| Course Hours | 14 | 2 | 28 | ||||
| Study Hours Out of Class | 14 | 4 | 56 | ||||
| Presentations / Seminar | 1 | 1 | 1 | ||||
| Homework Assignments | 1 | 2 | 2 | ||||
| Quizzes | 1 | 1 | 1 | ||||
| Midterms | 1 | 1 | 1 | ||||
| Final | 1 | 1 | 1 | ||||
| Total Workload | 90 | ||||||