Pharmacy
Bachelor TR-NQF-HE: Level 6 QF-EHEA: First Cycle EQF-LLL: Level 6

Course General Introduction Information

Course Code: ECZ421
Course Name: Pharmaceutical Chemistry IV
Course Semester: Spring
Course Credits:
ECTS
3
Language of instruction: TR-EN
Course Requirement:
Does the Course Require Work Experience?: No
Type of course: Necessary
Course Level:
Bachelor TR-NQF-HE:6. Master`s Degree QF-EHEA:First Cycle EQF-LLL:6. Master`s Degree
Mode of Delivery: Face to face
Course Coordinator : Prof. Dr. ŞEREF DEMİRAYAK
Course Lecturer(s): Prof. Dr. ŞEREF DEMİRAYAK
Course Assistants:

Course Purpose and Content

Course Objectives: Objective of this course is to teach the importance of chemical structure, synthesis methods, analysis, action mechanisms, structure-activity relationship and metabolism reactions of chemotherapeutics on the development of new chemotherapeutic drugs and new therapeutic approaches.
Course Content: The aim of this course is to give the basic theoretical knowledge of structures, synthesis, structure-activity relationships, mode of action, and biotransformations of chemotherapeutic agents; antibacterial drugs, antimycobacterial drugs, antifungal drugs, antiviral drugs, antiprotozoal drugs, antineoplastic agents, antiseptic and disinfectant compounds and vitamins.

Learning Outcomes

The students who have succeeded in this course;
1) To be able to interpret the basic principles of chemotherapy
2) Should be able to classify the antibacterial ,antifungal drugs and explain their mechanism of action.
3) Should be able to interpret the chemical mechanism of cancer formation
4) To be able to interpret the mechanism of action of antineoplastic compounds
5) To be able to interpret the mechanism of action of antiviral drugs
6) Should know the structures, synthesis methods, structure-activity relationships, biotransformations of chemotherapeutic drugs

Course Flow Plan

Week Subject Related Preparation
1) Antibacterial drugs, sulphonamides
2) Antimycobacterial drugs
3) Beta-lactam antibiotics
4) Beta-lactamase inhibitors, broad spectrum penicillin
5) Cephalosporins
6) Carbapenems, monobactams
7) Macrolids
8) Midterm exam
9) Bacterial protein synthesis inhibitors
10) DNA gyrase inhibitors
11) Antifungal drugs
12) Antiviral drugs
13) Anticancer drugs
14) Antiseptics and disinfectants
15) Thyroid drugs

Sources

Course Notes / Textbooks:
References: 1.An Introduction to Medicinal Chemistry, G.L.Patrick, 6. Baskı (2017) Oxford University Press.
2.Foye's Principles of Medicinal Chemistry
V. F. Roche ,S. W. Zito T. Lemke, D. A. Williams (2019) Walters Kluwer

Course - Learning Outcome Relationship

No Effect 1 Lowest 2 Medium 3 Highest
       
Program Outcomes Level of Contribution
1) Access, evaluate and apply up-to-date scientific knowledge in the field of pharmacy 5
2) It conveys information to patients, health personnel and society on all matters related to drugs. 5
3) Has the necessary knowledge about the therapeutic effects, drug forms, pharmacokinetic properties, stability and incompatibilities of drug active substances and can use this information. 5
4) Recognizes, controls and standardizes quality assurance issues and processes of all pharmaceutical-related products. 5
5) Has knowledge and equipment about the administration and use of the drug to the patient, advises on rational and safe drug use, and supports pharmacovigilance practices. 3
6) Has knowledge about the production and production technologies of natural and synthetic pharmaceutical raw materials. 5
7) Have knowledge about the concepts related to the functioning, maintenance and pathology of biological systems that form the basis of human health. 3
8) Has sufficient knowledge and application skills on research, development and production of pharmaceutical and cosmetic products. 5
9) Plans and implements all subjects within the scope of pharmacy services in the hospital. 4
10) Has knowledge about licensing conditions, data protection, patent and pharmacoeconomics in pharmaceuticals. 5
11) She/He is administratively and technically equipped in every field where the pharmacy profession is responsible by law, and produces solutions to problems in line with scientific data / evidence. 5
12) Combines basic and applied sciences with pharmacy profession practices and uses them in the field of pharmacy. 5
13) Has sufficient knowledge and application skills on physical, chemical, biological and toxicological analyzes of pharmaceutical, biotechnological and radiopharmaceutical products. 5
14) Acts in accordance with ethical and legal principles in the field of pharmacy. 5
15) Has the necessary competencies to work with colleagues and other health professionals in terms of communicative, managerial and social skills. 5
16) Provides consultancy on medicinal plants, herbal supplements and food supplements. 3
17) Knows pharmaceutical care practices, understands and evaluates drug interactions. 5
18) Knows the risks associated with the use of drugs and other chemical substances and laboratory practice. 5

Learning Activity and Teaching Methods

Anlatım
Bireysel çalışma ve ödevi
Course
Homework
Soru cevap/ Tartışma

Measurement and Evaluation Methods and Criteria

Yazılı Sınav (Açık uçlu sorular, çoktan seçmeli, doğru yanlış, eşleştirme, boşluk doldurma, sıralama)

Assessment & Grading

Semester Requirements Number of Activities Level of Contribution
Midterms 1 % 40
Final 1 % 60
total % 100
PERCENTAGE OF SEMESTER WORK % 40
PERCENTAGE OF FINAL WORK % 60
total % 100

İş Yükü ve AKTS Kredisi Hesaplaması

Activities Number of Activities Aktiviteye Hazırlık Aktivitede Harçanan Süre Aktivite Gereksinimi İçin Süre Workload
Course Hours 14 2 28
Study Hours Out of Class 14 4 56
Presentations / Seminar 1 1 1
Homework Assignments 1 2 2
Quizzes 1 1 1
Midterms 1 1 1
Final 1 1 1
Total Workload 90