Pharmacy | |||||
Bachelor | TR-NQF-HE: Level 6 | QF-EHEA: First Cycle | EQF-LLL: Level 6 |
Course Code: | ECZ422 | ||||
Course Name: | Pharmaceutical Chemistry Practice IV | ||||
Course Semester: | Spring | ||||
Course Credits: |
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Language of instruction: | TR-EN | ||||
Course Requirement: | |||||
Does the Course Require Work Experience?: | No | ||||
Type of course: | Necessary | ||||
Course Level: |
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Mode of Delivery: | |||||
Course Coordinator : | Prof. Dr. ŞEREF DEMİRAYAK | ||||
Course Lecturer(s): |
Prof. Dr. ŞEREF DEMİRAYAK |
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Course Assistants: |
Course Objectives: | The objective of this course is to teach the students the fundamentals of qualitative analyses of structural identification of active pharmaceutical ingredients (API) using the UV spectroscopy, infrared spectroscopy, nuclear magnetic resonance spectroscopy (1H and 13C), mass spectroscopy. |
Course Content: | The aim of this course is to give the basic information of UV spectroscopy, infrared spectroscopy, nuclear magnetic resonance spectroscopy (1H and 13 C) and Mass Spectrometry methods and structure determination of drug substances by spectral methods. |
The students who have succeeded in this course;
1) Should have knowledge about the spectral methods (UV, IR, NMR and mass) used to evaluate the structures of organic compounds. 2) Should be able to interpret the data obtained by spectral methods 3) Should be able to determine the chemical structures of drug active ingredients by spectral data 4) Evaluate the spectral data of active pharmaceutical ingredients registered in the Pharmacopoeia. 5) Should be evaluate UV, IR, NMR and mass spectra |
Week | Subject | Related Preparation |
1) | Fundamentals of structure identification of the organic compounds | |
2) | IR spectroscopy | |
3) | IR Spektroskopisi örnekler | |
4) | 4. H1 NMR and examples | |
5) | 1. H1 NMR and examples | |
6) | H1 NMR and examples | |
7) | C13 NMR | |
8) | midterm exam | |
9) | C13 NMR | |
10) | C13 NMR examples | |
11) | Mass spectrometry – Examples & Solutions | |
12) | Problem solving examples (Structural identification) | |
13) | Problem solving examples (Structural identification) | |
14) | Problem solving examples (Structural identification) | |
15) | Compensational Lab. |
Course Notes / Textbooks: | |
References: | 1. İlaçların Tanınması ve Kantitatif Tayini, Nedime Ergenç,Aysel Gürsoy, Öznur Ateş (1999).İstanbul Üniversitesi Yayınları 2. Organik Kimyada spektroskopik yöntemler. Ender Erdik. (2015) Gazi Kitabevi Yardımcı Kaynaklar Spectrometric Identification of Organic Compounds . R M. Silverstein, F X Webster, D. Kiemle, D L. Bryce . (2014) John Wiley |
No Effect | 1 Lowest | 2 Medium | 3 Highest |
Program Outcomes | Level of Contribution | |
1) | Access, evaluate and apply up-to-date scientific knowledge in the field of pharmacy | 5 |
2) | It conveys information to patients, health personnel and society on all matters related to drugs. | 5 |
3) | Has the necessary knowledge about the therapeutic effects, drug forms, pharmacokinetic properties, stability and incompatibilities of drug active substances and can use this information. | 3 |
4) | Recognizes, controls and standardizes quality assurance issues and processes of all pharmaceutical-related products. | 5 |
5) | Has knowledge and equipment about the administration and use of the drug to the patient, advises on rational and safe drug use, and supports pharmacovigilance practices. | 3 |
6) | Has knowledge about the production and production technologies of natural and synthetic pharmaceutical raw materials. | 5 |
7) | Have knowledge about the concepts related to the functioning, maintenance and pathology of biological systems that form the basis of human health. | 3 |
8) | Has sufficient knowledge and application skills on research, development and production of pharmaceutical and cosmetic products. | 5 |
9) | Plans and implements all subjects within the scope of pharmacy services in the hospital. | 3 |
10) | Has knowledge about licensing conditions, data protection, patent and pharmacoeconomics in pharmaceuticals. | 3 |
11) | She/He is administratively and technically equipped in every field where the pharmacy profession is responsible by law, and produces solutions to problems in line with scientific data / evidence. | 5 |
12) | Combines basic and applied sciences with pharmacy profession practices and uses them in the field of pharmacy. | 5 |
13) | Has sufficient knowledge and application skills on physical, chemical, biological and toxicological analyzes of pharmaceutical, biotechnological and radiopharmaceutical products. | 5 |
14) | Acts in accordance with ethical and legal principles in the field of pharmacy. | 5 |
15) | Has the necessary competencies to work with colleagues and other health professionals in terms of communicative, managerial and social skills. | 5 |
16) | Provides consultancy on medicinal plants, herbal supplements and food supplements. | 1 |
17) | Knows pharmaceutical care practices, understands and evaluates drug interactions. | 2 |
18) | Knows the risks associated with the use of drugs and other chemical substances and laboratory practice. | 5 |
Anlatım | |
Course | |
Labs | |
Rapor Yazma | |
Soru cevap/ Tartışma | |
Uygulama (Modelleme, Tasarım, Maket, Simülasyon, Deney vs.) |
Yazılı Sınav (Açık uçlu sorular, çoktan seçmeli, doğru yanlış, eşleştirme, boşluk doldurma, sıralama) | |
Uygulama | |
Raporlama |
Semester Requirements | Number of Activities | Level of Contribution |
Quizzes | 6 | % 60 |
Final | 1 | % 40 |
total | % 100 | |
PERCENTAGE OF SEMESTER WORK | % 60 | |
PERCENTAGE OF FINAL WORK | % 40 | |
total | % 100 |
Activities | Number of Activities | Aktiviteye Hazırlık | Aktivitede Harçanan Süre | Aktivite Gereksinimi İçin Süre | Workload | ||
Course Hours | 14 | 3 | 42 | ||||
Study Hours Out of Class | 10 | 1 | 10 | ||||
Quizzes | 5 | 1 | 5 | ||||
Midterms | 1 | 1 | 1 | ||||
Final | 1 | 1 | 1 | ||||
Total Workload | 59 |