Istanbul Health and Technology University INFORMATION PACKAGE / COURSE CATALOGUE
| Pharmacy | |||||
| Bachelor | TR-NQF-HE: Level 6 | QF-EHEA: First Cycle | EQF-LLL: Level 6 | ||
Course General Introduction Information
| Course Code: | ECZ113 | ||||
| Course Name: | Medical Biology and Genetics | ||||
| Course Semester: | Fall | ||||
| Course Credits: |
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| Language of instruction: | TR | ||||
| Course Requirement: | |||||
| Does the Course Require Work Experience?: | No | ||||
| Type of course: | Necessary | ||||
| Course Level: |
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| Mode of Delivery: | Face to face | ||||
| Course Coordinator : | MERVE ERKISA GENEL | ||||
| Course Lecturer(s): | Asst. Prof. MERVEE RKISA GENEL | ||||
| Course Assistants: |
Course Purpose and Content
| Course Objectives: | This course provides full examining and understanding for the basic concept of cell biology with the scope of cellular and genetics events from pharmaceutical studies perspective. |
| Course Content: | Students should be able to learn the basis of cell biology and understand the importance of intercellular interactions in the light of genetic science. Students should be able to combine all the knowledge from different lectures in this module as a pharmacist point of view. Moreover, this module provides a foundation knowledge of organismal mechanism and biology for the other pharmaceutical studies with the help of interactive assignments. |
Learning Outcomes
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The students who have succeeded in this course;
1) Should be able to know the origin, diversity, and classification criteria of the living 2) Should be able to learn the basics, structure and functioning of cell biology 3) Hücre zarı ve iskelet bileşenlerini bilebilmeli 4) Should be able to acknowledge the function of cell organelles and their interaction with each other x 5) Should be able to learn Endoplasmic reticulum and Golgi organelles and the relationship between endoplasmic reticulum and nucleus and protein trafficking all together with its outlines x 6) Should be able to know the importance of the intercellular communication from a pharmacist perspective with the important structures that enable intercellular communication 7) Should be able to know the cell cycle, cell divisions in detail and understand the importance of genetic diversity x 8) Should be able to know the factors of cell aging and the types of cell death 9) Should be able to understand cell energy metabolism reactions between various cell types 10) Should be able to understand how cell signalling mechanisms function and intercellular signal transmission is performed between different tissue and cell types 11) Should be able to understand the action mechanisms of specific hormones, the differences between intracellular receptors and cell surface receptors, and understand the importance of these mechanisms in terms of pharmaceutical studies. 12) Should be able to understand DNA replication, steps with its enzymes and its importance. Understand the factors that cause DNA damage and the functioning of certain repair mechanisms 13) Should be able to fully comprehend how information flows from DNA to protein, the steps of gene expression together with the post translational modification processes 14) Should be able to comprehend the epigenetic package and their importance in genotype-phenotype compatible prenatal and postnatal details. Must be able to know the basic mechanisms of cancer biology. 15) Sould be able to understand the important projects carried out recently, comprehend all the transferred information as a whole, and understand what pharmacogenetic studies are and the need for personalized drug production by integrating the transferred genetic and cell biology information. |
Course Flow Plan
| Week | Subject | Related Preparation |
| 1) | Concept of Cell Biology (Cell theory, life and cell types) | |
| 2) | Cell Structure and Functioning 1 (Cell membrane content functions and importance, Organelles, Protein traffic) | |
| 3) | Cell structure and functioning 2 (Organelles and nucleus) | |
| 4) | Intercellular communication (Intercellular connections, important proteins, Extracellular matrix) | |
| 5) | Transport in the cell membrane 1 (Transport dynamics, diffusion, passive transport and membrane proteins that assist in transport) | |
| 6) | Transport in the cell membrane 2 (Active transport and organism-bound examples, membrane pumps) Academic writing technique, scientific report writing technique, access to academic information and use of references training seminar | |
| 7) | Cell division (Cell cycle, mitosis, meiosis 1, meiosis 2, genetic diversity) | |
| 8) | MIDTERM | |
| 9) | Cell aging and cell death, Cell energy metabolism | |
| 10) | Intercellular stimulus transmission and stimulation mechanisms (Signal transmission, steroid hormone action mechanisms, cell surface receptors) | |
| 11) | Introduction to genetics and Basic Genetic Concepts 1 (Genes, genome, Nucleic acids, DNA Replication) | |
| 11) | Introduction to genetics and Basic Genetic Concepts 1 (Genes, genome, Nucleic acids, DNA Replication) | |
| 11) | Introduction to genetics and Basic Genetic Concepts 1 (Genes, genome, Nucleic acids, DNA Replication) | |
| 12) | Introduction to genetics and Basic Genetic Concepts 2 (DNA damage and repair, Transcription + Translation) | |
| 13) | Genetic Concepts (Genotype, phenotype relationship, Mendelian genetics) Genetic Material Disorders and Mutation Types | |
| 14) | Cancer biology, mechanism, Epigenetic mechanisms | |
| 15) | FINAL |
Sources
| Course Notes / Textbooks: | 1. Prof. Dr. Hasan Veysi Güneş, Moleküler Hücre Biyolojisi, İstanbul Tıp Kitabevleri, 5. Baskı 2018. 2. Prof. Dr. Halil Kasap, Tıbbi Biyoloji ve Genetik, Akademisyen Kitabevi, 3. Baskı 2020. Bruce Alberts, Essential Cell Biology, Garland Science, Fourth Edition, 2014. |
| References: | Bruce Alberts, Essential Cell Biology, Garland Science, Fourth Edition, 2014. Prof. Dr. Hasan Veysi Güneş, Moleküler Hücre Biyolojisi, İstanbul Tıp Kitabevleri, 5. Baskı 2018. Prof. Dr. Halil Kasap, Tıbbi Biyoloji ve Genetik, Akademisyen Kitabevi, 3. Baskı 2020. |
Course - Learning Outcome Relationship
| No Effect | 1 Lowest | 2 Medium | 3 Highest |
| Program Outcomes | Level of Contribution | |
| 1) | Access, evaluate and apply up-to-date scientific knowledge in the field of pharmacy | 3 |
| 2) | It conveys information to patients, health personnel and society on all matters related to drugs. | 3 |
| 3) | Has the necessary knowledge about the therapeutic effects, drug forms, pharmacokinetic properties, stability and incompatibilities of drug active substances and can use this information. | 3 |
| 4) | Recognizes, controls and standardizes quality assurance issues and processes of all pharmaceutical-related products. | 3 |
| 5) | Has knowledge and equipment about the administration and use of the drug to the patient, advises on rational and safe drug use, and supports pharmacovigilance practices. | 3 |
| 6) | Has knowledge about the production and production technologies of natural and synthetic pharmaceutical raw materials. | 3 |
| 7) | Have knowledge about the concepts related to the functioning, maintenance and pathology of biological systems that form the basis of human health. | 3 |
| 8) | Has sufficient knowledge and application skills on research, development and production of pharmaceutical and cosmetic products. | 3 |
| 9) | Plans and implements all subjects within the scope of pharmacy services in the hospital. | 3 |
| 10) | Has knowledge about licensing conditions, data protection, patent and pharmacoeconomics in pharmaceuticals. | 3 |
| 11) | She/He is administratively and technically equipped in every field where the pharmacy profession is responsible by law, and produces solutions to problems in line with scientific data / evidence. | 3 |
| 12) | Combines basic and applied sciences with pharmacy profession practices and uses them in the field of pharmacy. | 3 |
| 13) | Has sufficient knowledge and application skills on physical, chemical, biological and toxicological analyzes of pharmaceutical, biotechnological and radiopharmaceutical products. | 3 |
| 14) | Acts in accordance with ethical and legal principles in the field of pharmacy. | 3 |
| 15) | Has the necessary competencies to work with colleagues and other health professionals in terms of communicative, managerial and social skills. | 3 |
| 16) | Provides consultancy on medicinal plants, herbal supplements and food supplements. | 3 |
| 17) | Knows pharmaceutical care practices, understands and evaluates drug interactions. | 3 |
| 18) | Knows the risks associated with the use of drugs and other chemical substances and laboratory practice. | 3 |
Learning Activity and Teaching Methods
| Anlatım | |
| Beyin fırtınası /Altı şapka | |
| Bireysel çalışma ve ödevi | |
| Okuma | |
| Homework |
Measurement and Evaluation Methods and Criteria
| Yazılı Sınav (Açık uçlu sorular, çoktan seçmeli, doğru yanlış, eşleştirme, boşluk doldurma, sıralama) | |
| Homework |
Assessment & Grading
| Semester Requirements | Number of Activities | Level of Contribution |
| Committee | 42 | % 0 |
| Application | 42 | % 0 |
| Homework Assignments | 36 | % 0 |
| Midterms | 1 | % 50 |
| Final | 1 | % 50 |
| total | % 100 | |
| PERCENTAGE OF SEMESTER WORK | % 50 | |
| PERCENTAGE OF FINAL WORK | % 50 | |
| total | % 100 | |
İş Yükü ve AKTS Kredisi Hesaplaması
| Activities | Number of Activities | Aktiviteye Hazırlık | Aktivitede Harçanan Süre | Aktivite Gereksinimi İçin Süre | Workload | ||
| Course Hours | 14 | 4 | 56 | ||||
| Study Hours Out of Class | 6 | 6 | 36 | ||||
| Homework Assignments | 14 | 3 | 42 | ||||
| Midterms | 1 | 1 | 1 | ||||
| Final | 1 | 1 | 1 | ||||
| Total Workload | 136 | ||||||