Istanbul Health and Technology University INFORMATION PACKAGE / COURSE CATALOGUE
| Pharmacy (English) | |||||
| Bachelor | TR-NQF-HE: Level 6 | QF-EHEA: First Cycle | EQF-LLL: Level 6 | ||
Course General Introduction Information
| Course Code: | PHA113 | ||||
| Course Name: | Medical Biology and Genetics | ||||
| Course Semester: | Fall | ||||
| Course Credits: |
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| Language of instruction: | EN | ||||
| Course Requirement: | |||||
| Does the Course Require Work Experience?: | No | ||||
| Type of course: | Necessary | ||||
| Course Level: |
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| Mode of Delivery: | Face to face | ||||
| Course Coordinator : | Dr.Öğr.Üyesi GÜLDEN BUDAK | ||||
| Course Lecturer(s): | Dr. Gulden BUDAK | ||||
| Course Assistants: |
Course Purpose and Content
| Course Objectives: | This course provides full examining and understanding for the basic concept of cell biology with the scope of cellular and genetics events from pharmaceutical studies perspective. |
| Course Content: | Students should be able to learn the basis of cell biology and understand the importance of intercellular interactions in the light of genetic science. Students should be able to combine all the knowledge from different lectures in this module as a pharmacist point of view. Moreover, this module provides a foundation knowledge of organismal mechanism and biology for the other pharmaceutical studies with the help of interactive assignments. |
Learning Outcomes
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The students who have succeeded in this course;
1) Should be able to know the origin, diversity, and classification criteria of the living 2) Should be able to learn the basics, structure and functioning of cell biology 3) Should be able to acknowledge the cell membrane and skeletal components 4) Should be able to acknowledge the function of cell organelles and their interaction with each other 5) Should be able to learn Endoplasmic reticulum and Golgi organelles and the relationship between endoplasmic reticulum and nucleus and protein trafficking all together with its outlines 6) Should be able to know the importance of the intercellular communication from a pharmacist perspective with the important structures that enable intercellular communication 7) Should be able to know the cell cycle, cell divisions in detail and understand the importance of genetic diversity 8) Should be able to know the factors of cell aging and the types of cell death 9) Should be able to understand cell energy metabolism reactions between various cell types 10) Should be able to understand how cell signalling mechanisms function and intercellular signal transmission is performed between different tissue and cell types 11) Should be able to understand the action mechanisms of specific hormones, the differences between intracellular receptors and cell surface receptors, and understand the importance of these mechanisms in terms of pharmaceutical studies 12) Should be able to understand DNA replication, steps with its enzymes and its importance. Understand the factors that cause DNA damage and the functioning of certain repair mechanisms 13) Should be able to fully comprehend how information flows from DNA to protein, the steps of gene expression together with the post translational modification processes 14) Should be able to comprehend Mendelian Genetics and the effects of the rule of dominance on genotype and phenotype characters together with the concepts of heterozygous and homozygous alleles 15) Should be able to understand how various forms of mutations occur and understand certain types of chromosomal abnormalities, syndromes expressed as phenotypes, and the causes of these abnormalities. 16) Should be able to comprehend epigenetic mechanisms and their genotype-phenotype relationships together with their importance in the preparation and postpartum processes and should be able to know the basic mechanisms of cancer biology 17) Should be able to understand recent projects about pharmacogenetic studies and comprehend all the information explained in all lectures about cell biology and genetics |
Course Flow Plan
| Week | Subject | Related Preparation |
| 1) | Cell Biology Concept (Cell theory, vitality origin, cell types) | |
| 2) | Cell Structure and Functioning 1 (Plasma membrane content, functions and importance, organelles, protein trafficking) | |
| 3) | Cell Structure and Functioning 2 (Organelles and Nucleus) | |
| 4) | Intercellular communication (Intercellular connections, important proteins, Extracellular matrix) | |
| 5) | Transport across the plasma membrane 1 (Transport dynamics, diffusion, passive transport and membrane proteins related with the transport) | |
| 6) | Transport across the plasma membrane 2 (Active transport, membrane pumps, examples to transport events related with the different systems of an organism) Seminar about Academic writing technique, scientific report writing technique, access to academic knowledge and learning referencing technique. | |
| 7) | Cell division (Cell cycle, mitosis, meiosis 1, meiosis 2, genetic diversity) | |
| 8) | MIDTERM EXAM | |
| 9) | Aging, cell death and cell energy metabolism (Respiration and Photosynthesis) | |
| 10) | Cell Signalling Mechanisms (Signal transmission steroid hormone action mechanisms, cell surface receptors) | |
| 11) | Introduction to Genetics and Basic Genetic Concepts 1 (Genes, genome, Nucleic acids, DNA Replication) | |
| 12) | Introduction to Genetics and Basic Genetic Concepts 2 (DNA damage and repair, Transcription + Translation) | |
| 13) | Genetic Concepts (Genotype, phenotype relationship, Mendel genetics) Genetic Material Disorders and Mutation types | |
| 14) | Cancer Biology Mechanism and Epigenetics | |
| 15) | Genome projects, Pharmacogenetics and Stratified Medicine Approaches |
Sources
| Course Notes / Textbooks: | Presentations prepared from current text books and e-publications. |
| References: | The Cell: A Molecular Approach 8th Edition, Geoffrey Cooper, Oxford Publication, Concepts of Genetics, 12th edition, William S Klug, Michael Cummings, Michael A Palladino ,Darrell Killian, Pearson publication |
Course - Learning Outcome Relationship
| No Effect | 1 Lowest | 2 Medium | 3 Highest |
| Program Outcomes | Level of Contribution |
Learning Activity and Teaching Methods
| Anlatım | |
| Course | |
| Okuma | |
| Soru cevap/ Tartışma |
Measurement and Evaluation Methods and Criteria
| Yazılı Sınav (Açık uçlu sorular, çoktan seçmeli, doğru yanlış, eşleştirme, boşluk doldurma, sıralama) |
Assessment & Grading
| Semester Requirements | Number of Activities | Level of Contribution |
| Homework Assignments | 6 | % 15 |
| Midterms | 1 | % 30 |
| Final | 1 | % 55 |
| total | % 100 | |
| PERCENTAGE OF SEMESTER WORK | % 45 | |
| PERCENTAGE OF FINAL WORK | % 55 | |
| total | % 100 | |
İş Yükü ve AKTS Kredisi Hesaplaması
| Activities | Number of Activities | Aktiviteye Hazırlık | Aktivitede Harçanan Süre | Aktivite Gereksinimi İçin Süre | Workload | ||
| Course Hours | 14 | 3 | 42 | ||||
| Study Hours Out of Class | 14 | 3 | 42 | ||||
| Homework Assignments | 6 | 6 | 36 | ||||
| Midterms | 1 | 1 | 1 | ||||
| Final | 1 | 1 | 1 | ||||
| Total Workload | 122 | ||||||