Medicine (English)
Bachelor TR-NQF-HE: Level 7 QF-EHEA: Second Cycle EQF-LLL: Level 7

Course General Introduction Information

Course Code: MED-200
Course Name: BASIC MEDICAL SCIENCES-II
Course Semester: Fall
Course Credits:
ECTS
56
Language of instruction: EN
Course Requirement:
Does the Course Require Work Experience?: No
Type of course: Necessary
Course Level:
Bachelor TR-NQF-HE:7. Master`s Degree QF-EHEA:Second Cycle EQF-LLL:7. Master`s Degree
Mode of Delivery: Face to face
Course Coordinator : Dr.Öğr.Üyesi KADİR DAŞTAN
Course Lecturer(s): Prof. Dr. Nihal Salmayenli, Doç Dr. İlknur Bingül Prof. Dr. Nihal Salmayenli, Doç . Dr. Fatih Aydın, Ozan Toraman, Doç. Dr. Özcan Gayretli, Dr. Öğr. Üyesi Osman Coşkun, Dr. Öğr. Üyesi Tayfun Dikmen, Prof. Dr. Derya Aydın, Prof. Dr. M. Can Akyolcu, Prof. Dr. Hasan Hakan Bozkurt, Prof. Dr. Evin Ademoğlu, Prof. Dr. Pervin Vural, Prof. Dr. Ayşin Kale, Dr. Öğr. Üyesi Yeşin Üresin, Dr. Öğr. Üyesi Selçuk Şen, Prof. Dr. Canan Alatlı
Course Assistants:

Course Purpose and Content

Course Objectives: The aim of this board is to learn the basics of clinical sciences, as well as cardiovascular, hematopoietic and respiratory systems, gastrointestinal system and metabolism, nervous system and sensory organs, endocrine and urogenital systems.
Course Content: It consists of a total of 5 committee: Cardiovascular, Hematopoietic, and Respiratory System Committee, Gastrointestinal System and Metabolism Committee, Nervous System and Sense Organs Committee, Endocrine and Urogenital System Committee, Clinical Sciences Entrance Committee

Learning Outcomes

The students who have succeeded in this course;
1) C01 To be able to explain the histological, anatomical, biochemical and physiological features of the respiratory and circulatory system. C02 To be able to comprehend the physical and functional properties and components of blood, as well as the types, functions and production processes of blood cells. C03 To be able to interpret the histological and anatomical features of the digestive system, as well as the physiological and biochemical mechanisms associated with the digestion and absorption processes of food C04 To understand the principles of working with biological materials, to prepare media and to evaluate bacteria according to their culture and staining properties. C05 To explain the histology, anatomy, physiology and biochemistry of the nervous system. C06 To be able to grasp the senses of sight, hearing, taste, smell and touch and also evaluate various reflex mechanisms C07 To be able to explain the features of central and peripheral nervous systems, regulation of pain, control of motor movements, learning and memory, EEG and sleep. C08 To be able to explain the macroscopic and microscopic structure of the organs that make up the excretory system, their location in the abdomen and their neighborhood relations. C09 To be able to comprehend glomerular filtration, tubular reabsorption and secretion mechanisms and micturition reflex in kidney. C10 To be able to explain the anatomical and histological features of the organs that make up the endocrine and reproductive systems. C11 To be able to interpret the general and structural properties of hormones, their synthesis and metabolism, the processes of change in the body and their mechanisms of action. C12 To be able to comprehend the importance of using cadavers in anatomy education while learning the characteristics of the organism. C13 To be able to apply basic biostatistical methods during scientific research C14 To be able to comprehend the importance of microscope use in histological evaluations
1) At the end of the Cardiovascular, Hematopoietic and Respiratory System course committee Year II Students; 1. Will be able to detect and analyze vital signs correctly, 2. Will be able to evaluate heart sounds correctly, 3. Will be able to measure blood pressure and pulse, 4. Will be able to prepare media, culture and microscope in the laboratory will be able to use it, 5. Will be able to prepare preparations for erythrocyte and leukocyte counts and evaluate them under microscope, 6. will be able to perform and evaluate respiratory function tests. At the end of the Gastrointestinal System and Metabolism course board, Term II students; 1. The organs, glands and other formations of the digestive system on the model will be able to show and name them, 2. Tongue, salivary glands, lips, esophagus, stomach, small and large intestines and liver, will be able to describe the structures of pancreas and gallbladder under light microscope.
1) To be equipped with high level, up-to-date and comprehensive knowledge including basic sciences, clinical sciences and behavioural sciences and their relations with each other.
1) Knowledge: To be equipped with high level, up-to-date and comprehensive knowledge including basic sciences, clinical sciences and behavioural sciences and their relations with each other. Skills: 1. Preventive medicine: To have the knowledge and skills necessary for the protection and promotion of health 2: To be equipped with the best level of examination, intervention, etc. skills in order to make appropriate diagnosis and treatment approach 3: To be able to communicate effectively by empathising with patients, relatives, colleagues and colleagues 4: To be able to analyse and synthesise information Competence Due to its structure, the programme includes basic and clinical sciences as well as the latest scientific developments in these fields. When evaluated in terms of national physician training programmes and competencies in the field of health, our programme comes to the forefront because it offers courses in many basic areas, especially in the step of "comprehending the concepts and relationships between concepts related to the field, based on the competencies gained in secondary education". In addition, it offers a qualified education in all areas related to curriculum and strategies, understanding the nature of knowledge, understanding the developmental characteristics of students, using information resources, individual and group work, communication and social competence and health field knowledge. Graduates of the programme are able to implement, plan, supervise and restructure preventive and curative health services at national and international level in communities and individuals with different socio-cultural, ethnic and economic structures with their services related to medical sciences and health fields, in all kinds of public or private, individual or legal entities.
1) Due to its structure, the programme includes basic and clinical sciences as well as the latest scientific developments in these fields. When evaluated in terms of national physician training programmes and competencies in the field of health, our programme comes to the forefront because it offers courses in many basic areas, especially in the step of "comprehending the concepts and relationships between concepts related to the field, based on the competencies gained in secondary education". In addition, it offers a qualified education in all areas related to curriculum and strategies, understanding the nature of knowledge, understanding the developmental characteristics of students, using information resources, individual and group work, communication and social competence and health field knowledge. Graduates of the programme are able to implement, plan, supervise and restructure preventive and curative health services at national and international level in communities and individuals with different socio-cultural, ethnic and economic structures with their services related to medical sciences and health fields, in all kinds of public or private, individual or legal entities.
2) Preventive medicine: To have the knowledge and skills necessary for the protection and promotion of health
2) C01 To be able to explain the histological, anatomical, biochemical and physiological features of the respiratory and circulatory system. C02 To be able to comprehend the physical and functional properties and components of blood, as well as the types, functions and production processes of blood cells. C03 To be able to interpret the histological and anatomical features of the digestive system, as well as the physiological and biochemical mechanisms associated with the digestion and absorption processes of food C04 To understand the principles of working with biological materials, to prepare media and to evaluate bacteria according to their culture and staining properties. C05 To explain the histology, anatomy, physiology and biochemistry of the nervous system. C06 To be able to grasp the senses of sight, hearing, taste, smell and touch and also evaluate various reflex mechanisms C07 To be able to explain the features of central and peripheral nervous systems, regulation of pain, control of motor movements, learning and memory, EEG and sleep. C08 To be able to explain the macroscopic and microscopic structure of the organs that make up the excretory system, their location in the abdomen and their neighborhood relations. C09 To be able to comprehend glomerular filtration, tubular reabsorption and secretion mechanisms and micturition reflex in kidney. C10 To be able to explain the anatomical and histological features of the organs that make up the endocrine and reproductive systems. C11 To be able to interpret the general and structural properties of hormones, their synthesis and metabolism, the processes of change in the body and their mechanisms of action. C12 To be able to comprehend the importance of using cadavers in anatomy education while learning the characteristics of the organism. C13 To be able to apply basic biostatistical methods during scientific research C14 To be able to comprehend the importance of microscope use in histological evaluations
2) 1. Preventive medicine: To have the knowledge and skills necessary for the protection and promotion of health
3) C01 To be able to explain the histological, anatomical, biochemical and physiological features of the respiratory and circulatory system. C02 To be able to comprehend the physical and functional properties and components of blood, as well as the types, functions and production processes of blood cells. C03 To be able to interpret the histological and anatomical features of the digestive system, as well as the physiological and biochemical mechanisms associated with the digestion and absorption processes of food C04 To understand the principles of working with biological materials, to prepare media and to evaluate bacteria according to their culture and staining properties. C05 To explain the histology, anatomy, physiology and biochemistry of the nervous system. C06 To be able to grasp the senses of sight, hearing, taste, smell and touch and also evaluate various reflex mechanisms C07 To be able to explain the features of central and peripheral nervous systems, regulation of pain, control of motor movements, learning and memory, EEG and sleep. C08 To be able to explain the macroscopic and microscopic structure of the organs that make up the excretory system, their location in the abdomen and their neighborhood relations. C09 To be able to comprehend glomerular filtration, tubular reabsorption and secretion mechanisms and micturition reflex in kidney. C10 To be able to explain the anatomical and histological features of the organs that make up the endocrine and reproductive systems. C11 To be able to interpret the general and structural properties of hormones, their synthesis and metabolism, the processes of change in the body and their mechanisms of action. C12 To be able to comprehend the importance of using cadavers in anatomy education while learning the characteristics of the organism. C13 To be able to apply basic biostatistical methods during scientific research C14 To be able to comprehend the importance of microscope use in histological evaluations
3) To be equipped with the best level of examination, intervention, etc. skills in order to make appropriate diagnosis and treatment approach
3) To be equipped with the best level of examination, intervention, etc. skills in order to make appropriate diagnosis and treatment approach
4) C01 To be able to explain the histological, anatomical, biochemical and physiological features of the respiratory and circulatory system. C02 To be able to comprehend the physical and functional properties and components of blood, as well as the types, functions and production processes of blood cells. C03 To be able to interpret the histological and anatomical features of the digestive system, as well as the physiological and biochemical mechanisms associated with the digestion and absorption processes of food C04 To understand the principles of working with biological materials, to prepare media and to evaluate bacteria according to their culture and staining properties. C05 To explain the histology, anatomy, physiology and biochemistry of the nervous system. C06 To be able to grasp the senses of sight, hearing, taste, smell and touch and also evaluate various reflex mechanisms C07 To be able to explain the features of central and peripheral nervous systems, regulation of pain, control of motor movements, learning and memory, EEG and sleep. C08 To be able to explain the macroscopic and microscopic structure of the organs that make up the excretory system, their location in the abdomen and their neighborhood relations. C09 To be able to comprehend glomerular filtration, tubular reabsorption and secretion mechanisms and micturition reflex in kidney. C10 To be able to explain the anatomical and histological features of the organs that make up the endocrine and reproductive systems. C11 To be able to interpret the general and structural properties of hormones, their synthesis and metabolism, the processes of change in the body and their mechanisms of action. C12 To be able to comprehend the importance of using cadavers in anatomy education while learning the characteristics of the organism. C13 To be able to apply basic biostatistical methods during scientific research C14 To be able to comprehend the importance of microscope use in histological evaluations
4) To be able to communicate effectively by empathising with patients, relatives, colleagues and colleagues
5) Access to information
5) C01 To be able to explain the histological, anatomical, biochemical and physiological features of the respiratory and circulatory system. C02 To be able to comprehend the physical and functional properties and components of blood, as well as the types, functions and production processes of blood cells. C03 To be able to interpret the histological and anatomical features of the digestive system, as well as the physiological and biochemical mechanisms associated with the digestion and absorption processes of food C04 To understand the principles of working with biological materials, to prepare media and to evaluate bacteria according to their culture and staining properties. C05 To explain the histology, anatomy, physiology and biochemistry of the nervous system. C06 To be able to grasp the senses of sight, hearing, taste, smell and touch and also evaluate various reflex mechanisms C07 To be able to explain the features of central and peripheral nervous systems, regulation of pain, control of motor movements, learning and memory, EEG and sleep. C08 To be able to explain the macroscopic and microscopic structure of the organs that make up the excretory system, their location in the abdomen and their neighborhood relations. C09 To be able to comprehend glomerular filtration, tubular reabsorption and secretion mechanisms and micturition reflex in kidney. C10 To be able to explain the anatomical and histological features of the organs that make up the endocrine and reproductive systems. C11 To be able to interpret the general and structural properties of hormones, their synthesis and metabolism, the processes of change in the body and their mechanisms of action. C12 To be able to comprehend the importance of using cadavers in anatomy education while learning the characteristics of the organism. C13 To be able to apply basic biostatistical methods during scientific research C14 To be able to comprehend the importance of microscope use in histological evaluations
6) Mental skills: To be able to analyse and synthesise information
6) C01 To be able to explain the histological, anatomical, biochemical and physiological features of the respiratory and circulatory system. C02 To be able to comprehend the physical and functional properties and components of blood, as well as the types, functions and production processes of blood cells. C03 To be able to interpret the histological and anatomical features of the digestive system, as well as the physiological and biochemical mechanisms associated with the digestion and absorption processes of food C04 To understand the principles of working with biological materials, to prepare media and to evaluate bacteria according to their culture and staining properties. C05 To explain the histology, anatomy, physiology and biochemistry of the nervous system. C06 To be able to grasp the senses of sight, hearing, taste, smell and touch and also evaluate various reflex mechanisms C07 To be able to explain the features of central and peripheral nervous systems, regulation of pain, control of motor movements, learning and memory, EEG and sleep. C08 To be able to explain the macroscopic and microscopic structure of the organs that make up the excretory system, their location in the abdomen and their neighborhood relations. C09 To be able to comprehend glomerular filtration, tubular reabsorption and secretion mechanisms and micturition reflex in kidney. C10 To be able to explain the anatomical and histological features of the organs that make up the endocrine and reproductive systems. C11 To be able to interpret the general and structural properties of hormones, their synthesis and metabolism, the processes of change in the body and their mechanisms of action. C12 To be able to comprehend the importance of using cadavers in anatomy education while learning the characteristics of the organism. C13 To be able to apply basic biostatistical methods during scientific research C14 To be able to comprehend the importance of microscope use in histological evaluations

Course Flow Plan

Week Subject Related Preparation
1) Medical Biochemistry Functions of hemoproteins (Properties of the porphyrin ring) 1 Porphyrins and heme synthesis 1 Bilirubin metabolism (Degradation of the Heme ring) 1 Heme synthesis and degradation disorders 1 Hemoglobin variants and abnormal hemoglobins 1 Biochemistry of erythrocytes 1 Clinical Biochemistry Laboratory Approach to Anemia 1 Biochemistry of the endothelium 1 The process of atherosclerosis development 1
2) Biophysics Recent advances and developments in stem cell technology 1 Structure and function interaction in the circulatory system 1 The effect of blood pressure and blood flow resistance (“Shear Stress”) on plaque formation and rupture 1
3) Physiology 1-Physical composition of blood and general functional properties of plasma components 1 2-Hematopoiesis: erythropoiesis 1 3-Erythrocyte functions - regulation of erythrocyte life and hemolysis 1 4-Anemia Physiopathology and blood groups 1 5-Hemostasis 1 6-Coagulation 1 7-Regulation of endothelium and coagulation 1 8-Production of immune system cells (Hematopoiesis) 1 9-MHC and antigen presentation 1 10-Encounter of the antigen with the adaptive immune system 1 11-Lymphocyte development and maturation 1 12-The formation of immune diversity - Receptors 1 13-Lymphocyte activation 1 14-CD4+ T cell development and functions 1 15-CD8+ T cell development and functions 1 16-Regulation of immune response 1 1-Physiology of the Cardiac Muscle 1 2-Rhythmic Stimulation of the Heart 1 3-Excitation conduction system of the heart 1 4-Normal ECG 1 5-ECG changes 1 6-Heart cycle and heart sounds / 1 7-Pressure changes during the cardiac cycle 1 8-Extrinsic regulation of the heart's pumping function 1 9-Intrinsic regulation of the heart's pumping function 1 10-Cardiac output - venous return and its regulations 1 11-Measurement and regulation of arterial blood pressure 1 12-Cardiovascular adaptation in health and disease 1 13-Capillary circulation and lymphatic system 1 14-Roaming from special areas 1 15-Local and humoral control of blood flow by tissues 1 LAB 1) Blood physiology 2)Circulatory physiology 4
4) Anatomy 1-General information on circulatory system anatomy 1 2- External and internal appearance of the heart 1 3-Ventricles and atriums 1 4-The structure of the heart and its conduction system 1 5-Vessels and nerves of the heart 1 6-Arteries and truncus pulmonalis 1 7-Aorta 1 8-Head and neck arteries 1 9-Upper extremity arteries 1 10-Trunk arteries 1 *Pelvic arteries 1 11-Lower extremity arteries I 1 *Lower extremity arteries II 1 13-Head-neck veins 1 12-Veins and upper extremity veins 1 14-Trunk and lower extremity veins 1 15-Head-neck and upper extremity lymphatics 1 16-Trunk and lower extremity lymphatics 1 17-Regio axilla 1 LAB 13
5) Histology and Embryology Blood Tissue 1 Introduction to Lymphoid Tissue Histology 1 Histology of Lymphoid Organs I 1 Histology of Lymphoid Organs II 1 Histology of Arteries, Veins, Capillaries and Lymphatic Ducts I 1 Histology of Arteries, Veins, Capillaries and Lymphatic Ducts II 1 Histology of Heart 1 Development of Endothelium 1 Development of Heart 1 Development of Arteries, Veins, Capillaries and Lymphatic Ducts 1 Fetal Circulation 1 LAB: 1-Blood, Arteries and Veins 2- Heart and Lymphoid Organs 4
6) Medical Microbiology Introduction to medical microbiology 1 Introduction to bacteriology 2 Introduction to virology 2 Introduction to mycology 1 Introduction to parasitology 1 Host – microbe relationships, virulence 1 microbial metabolism 1 microbial genetics 1 Introduction to immunology 1 Sterilization - Disinfection 1
7) Anatomy 1-Thorax anatomy 1 2-Introduction to respiratory system anatomy 1 3-Larynx 1 4-Trachea Bronchi 1 5-Lungs 1 7-Mediastinum 1 6-Pleura 1 8-Respiratory system topographic anatomy 1 LAB 8 6
8) Medical Biochemistry 1-Use of oxygen in the cell and reactions requiring oxygen 1 2-Mitochondrial respiration, ATP synthesis and control in mitochondria 1 Biophysics 1-Respiratory dynamics - gas laws related to breathing 2 2-Volume-Pressure Changes During Respiration 2 3-Bioenergetics of cell respiration 2
9) Physiology 1-Organization of the Respiratory System - mucociliary mechanism 1 2-Alveolar ventilation and pulmonary circulation 1 3-Pressure Changes in the Pleura and Respiratory Cycle 1 4-Respiratory mechanics, diaphragm and respiratory muscles 1 5-Regulation of bronchial tone - ventilation-perfusion matching 1 6-Diffusion of Oxygen and Carbon Dioxide in Respiratory Membranes 1 7- Transport of Oxygen and Carbon Dioxide in Blood and Body Fluids 1 8-Respiration Regulation I 1 9-Respiration Regulation II 1 10-Respiratory Function Tests 1 11-Respiratory regulation in acid-base balance 1 LAB 1)Pulmoner function tests
10) Histology and Embryology 1-Development of Broncho-pharengeal Complex I 1 1-Development of Broncho-pharengeal Complex II 1 3-Development of Face and Upper Respiratory Tract 1 4-Development of Respiratory System 1 5-Introduction to Respiratory System Histology 1 6-Extrapulmonary and intrapulmonary Respiratory Tracts 1 7-Structure of Alveole, Pulmonary Circulation, and Pleura 1 LAB: Respiratory System 2 Medical Microbiology Innate immunity 2 Antigen processing, presentation to lymphocytes 1 Recognition of antigen by adaptive immunity system 1
11) Medical Biochemistry 1-Basic functions of metabolism 1 2-Glucose homeostasis 1 3-Indirect oxidation of glucose 1 4-Direct oxidation of glucose 1 5-Glycolysis 1 6-Gluconeogenesis 1 7-Glycogen metabolism 1 8-Hormonal control in carbohydrate metabolism 1 9-Monitoring carbohydrate metabolism in the laboratory 1 10-Overview of lipid metabolism 1 11-Lipoproteins structure and classification 1 12-Chylomicron VLDL and HDL 1 13-Lipolysis and fatty acid oxidation 1 14-Synthesis and use of ketone bodies 1 15-Fatty acid synthesis and lipogenesis 1 16-Cholesterol metabolism 1 17-Obesity biochemistry 1 18-Introduction to protein metabolism 1 19-Distribution of amino acids in the body and ways of use 1 20-Ammonia metabolism 1 21-Urea synthesis and regulation 1 22-Biological amines (Polyamines) 1 23-Methyl transfer - Mechanism of hyperhomocysteinemia 1 24-The importance of aromatic amino acids in the organism 1 25-Metabolism and defects of aromatic amino acids in the organism 1 26-Depoisonization reactions I 1 27-Depoisonization reactions II 1 28-Metabolic changes in the stages of life 1 1-Nutritional importance and classification of bioelements 1 2-Macro Elements 1 3-Trace elements I 1 4-Trace elements II 1 5-Ultra trace elements 1 LAB 1- metabolism I 2- Metabolism II 2
12) Physiology 1-Organization of the gastrointestinal (GI) system - Structural features of the GI tract muscles 1 2-Neural and hormonal control of GI function 1 3-Motility in the GI system - chewing, swallowing and esophageal motility 1 4-Stomach motility and gastric emptying mechanism Small and large intestine motility and defecation 1 5-Secretory function of the GI system - gastric secretion and HCL secretion mechanism 1 6-Gastric mucosal barrier (Exocrine secretion and function of the pancreas 1 7-Bile secretion from the liver and the function of bile and gallbladder Small and large intestine secretions 1 8-Digestion and absorption mechanisms in the GI tract 1
13) Anatomy 1-Abdomen Anatomy 1 2-Introduction to digestive system anatomy 1 3-Cavum oris 1 4-Pharynx 1 5-Esophageal stomach 1 6-Intestinum tenue 1 7-Intestinum crassum 1 8-Rectum canalis analis 1 9-Liver bile ducts and bladder 1 10-Pancreas - salivary glands 1 11-Peritoneum 1 1 12-Peritoneum 2 1
14) Histology and Embryology 1-Development of Digestive System 1 2-Development of Liver and Gallbladder 1 3-Digestive System Histology (Histology of Lip, Cheek and Palate ) 1 Histology of Salivary Glands and Esophagus 1 6-Histology of Stomach 1 7-Histology of Small Intestine 1 8-Histology of Large Intestine 1 9-Histology of Liver and Gallbladder 1 10- Histology of Pancreas 1 LAB: 1-Salivary Glands, Tongue, Esophagus 2-Stomach, Pancreas 3-Small and Large Intestines, Liver, Gallbladder 5 TOTAL HOURS 9 5 Medical Microbiology Cellular immunity 2 Humoral immunity, Antibodies 2 Autoimmunity, tolerance - Hypersensitivity reactions 1 Immunodeficiency – Tumor and transplant immunology 1
15) Medical Biochemistry 1-Water metabolism 1 2-Body fluids 1 3-Electrolyte metabolism 1 4-Physical and chemical properties of urine 1 5-The role of buffer systems in acid-base balance 1 6-Molecular mechanisms that ensure acid-base balance 1 7-Evaluation of pathologies seen in urine analysis 1 8-Kidney function tests 1 9-Biochemistry of female sex hormones 1 10-Biochemistry of male sex hormones 1 11-Non-protein nitrogenous compounds of blood 1 12-Placenta - amniotic fluid - cord blood biochemistry 1 1-Biochemical properties and classification of hormones 1 2-Mechanisms of action of protein-based hormones 1 3-Definition of Local Hormones - synthesis and metabolism 1 4-Mechanisms of action of steroid hormones 1 5-Hypothalamic and pituitary hormones I 1 6-Hypothalamic and pituitary hormones II 1 7-Thyroid hormones 1 8-Parathyroid hormone structure 1 9-Pancreatic hormones 1 10-Synthesis of adrenal hormones - Cortex 1 11-Synthesis of adrenal hormones - Medulla 1 12-Kidney and Gastrointestinal System Hormones 1
16) Physiology 1-Control of Pituitary Secretion by the Hypothalamus 1 2-Posterior pituitary hormones and their functions (ADH and Oxytocin) 1 3-Anterior pituitary hormones and their functions (Growth Hormone) 1 4-Functions of thyroid gland hormones 1 5-Functions of parathyroid gland hormones 1 6-Functions of pancreatic gland hormones - I 1 7-Functions of pancreatic gland hormones - II 1 8-Function of adrenal gland cortex hormones 1 9-Function of adrenal medulla hormones 1 1-Introduction to kidney physiology 1 2-Glomerular filtration mechanism 1 3-Renal blood flow and autoregulation 1 4-Function of kidney tubules 1 5-Clearance concept 1 6- Urine concentration mechanism-diuretics 1 7-Reproductive health 1 8-Pre-puberty reproductive physiology and control of puberty 1 9-Male reproductive physiology and sexual activity 1 10-Female physiology before pregnancy and menopause 1 11-Regulation of the menstrual cycle in women 1 12-Pregnancy - Birth and lactation physiology 1
17) Histology and Embryology 1-Embryology and Histology of Hyphophyseal Gland 1 2-Cell Types of Hyphopyseal Gland 1 3-Histological Structure of Anterior and Posterior Hypophysis, and Pineal Gland 1 4-Embryology and Histology of Tyroid and Paratyroid Glands 1 5-Embryology and Histology of Endocrine Pancreas 1 6-Embryology and Histology of Adrenal Glands 1 1-Development of Urinary System 1 2-Introduction to Urinary System Histology 1 3-Histology of Kidney- Structure of Nephron 1 4-Tubuli renalis 1 5-Urinary Tracts 1 6-Histology of Testis 2 7-Histology of Male Genital Ducts 1 8-Histology of Accesory Genital Glands and Penis 1 9-Histology of Ovary 2 10-Histology of Tuba Uterina, Uterus, Cervix and Vagina 1 11-Histology of Female External Genitalia, Mammary Gland, and Placenta 1 12-Development of Male Genital System 1 13-Development of Female Genital System 1
18) Anatomy 1-Introduction to urogenital system - External appearance of the kidneys 1 2-Posterior-anterior aspect of the kidneys / Prof.Dr. Ayşin KALE (Dr. Lecturer Osman COŞKUN) 1 3-Renal vascular system - nerves - lymph and anomalies 1 4-Anatomy of the collecting system of the kidney (calices and pelvis renalis) ureter 1 5-Vesica urinaria - neighborhoods (Vessels and nerves 1 6-Urethra 1 7-Abdominal walls anatomy 1 8-Male genital organs - testicles - epididymis 1 9-Sperm tracts and penis anatomy 1 10-Scrotum (Prostate - glandula bulbouretralis anatomy 1 11-Female genital organs - ovaries - tuba uterina 1 12-Uterus and vagina 1 13-Female external genital organs and specific glands 1 14-Regio inguinalis 1 15-Perineum 1 LAB 6
19) Anatomy 1-Introduction to central nervous system anatomy 1 2-Spinal Cord I 1 3-Spinal Cord II 1 4-Bulbus 1 5-Pons 1 6-Mesencephalon 1 7-Cerebellum 1 8-Hypothalamus - pituitary gland - glandula pinealis 1 9-Cerebrum 1 10-Cerebral hemispheres - basal ganglia 1 11-Functional localizations of cerebral cortex 1 12-Formatio reticularis and limbic system 1 13-Brain blood circulation 1 14-Leading roads 1 15-Descending roads 1 16-Meninges 1 17-Ear anatomy I 1 18-Ear anatomy II 1 19-Ear anatomy III 1 20-Eye anatomy I 1 21-Eye anatomy II 1 22-Introduction to peripheral nervous system anatomy 1 23-Plexus cervicalis 1 24-Plexus brachialis 1 1 25-Plexus brachialis 2 1 26-Thoracic spinal nerves 1 27-Plexus lumbalis 1 28-Plexus sacralis (Pudendalis - coccygeus 1 29-Head pairs 1 - 2 - 3 1 30-Head pairs 4 - 5 - 6 1 31-Head pairs 7 - 8 - 9 1 32-Head pairs 10 - 11 - 12 1 33-Nervous System and Acupuncture points 1 34-Autonomic nervous system I 1 38-Eye anatomy III 1 35-Autonomic nervous system II 1 36-Autonomic nervous system III 1 37-Autonomic nervous system IV 1 41-Regiones capitis- 1 1 42-Regiones capitis- 2 1 43-Cervical triangles 1 44-Cervical compartments 1 39-Skin anatomy general information 1 40-Skin appendages and breasts 1 LAB
20) Biophysics 1-Transduction features in the example of hearing and vision systems 1 2-Photoreceptors and translation (transduction) 1 3-Processing of sound waves in the ear 1 4-Biophysics of Hearing 1 5-Electroencephalogram (EEG) basic principles 2 6- Evoked potentials 2 LAB TOTAL HOURS 8 Physiology 1-Organization of the Nervous System - Basic Functions of Synapses 1 2-Sensory Receptors 1 3-Neuron Circuits in Processing Information 1 4-Somatic Senses 1 6-Structure of the eye and retina physiology 1 5-Visual optics and image formation 1 8-Color vision and volume vision 1 10-Transmission of sound in the ear and hearing tests 1 9-Functional structure of the ear 1 11-Senses of taste and smell 1 12-Motor functions of the spinal cord 1 13-Spinal cord reflexes 1 14-Spinal Shock and Medulla Spinalis Damages 1 15-Cortical Control of Motor Function 1 16-Contributions of the Cerebellum to General Motor Control 1 7-Photochemistry and neurophysiology of vision 1 17- Control of Motor Function by the Brainstem 1 18- Contributions of Basal Ganglia to General Motor Control 1 19-Cerebral blood flow - Blood-Brain Barrier 1 20-Cerebrospinal fluid and brain metabolism 1 21-Limbic system 1 22-Hypothalamus 1 23-Regulation of metabolism and body temperature 1 24-Brain Cortex 1 25-Mental functions of the brain - learning and memory 1 26-Activity states of the brain-Sleep, brain waves, epilepsy, psychoses 1 27-Autonomic Nervous System I 1 28-Autonomic Nervous System II 1 29-Damage and Regeneration in the Nervous System 1 30-Methods to Measure Brain Functions 1 LAB 8
21) Histology and Embryology 1-Development of Eye 1 2-Histology of Cornea, Sclera, Iris, Ciliary Body, and Choroid 1 3-Histology of Retina 1 4-Development of Ear 1 5-Histology of Inner Ear 1 6-Histology of Middle Ear and External Ear 1 7-Embryology and Histology of Medulla spinalis 1 8-Development of Nervous system-Neurulation 1 9-Development of Prosencephalon, Mesencephalon, and Rhombencephalon 1 10-Development of Peripheral and Autonomic Nervous Systems 1 11-Histology of Peripheral and Autonomic Nervous Systems 1 12-Embryology and Histology of Cerebellum 1 13-Histology of Pons and Medulla Oblongata 1 14-Histology Of Cerebrum 2 LAB: 1- Nervous System I 2- Nervous System II 4
22) Medical Microbiology 1-Microorganism-human interactions and normal body flora 1 2-Staphylococcus - Streptococcus and Enterococcus genera 1 4-Enterobacteriaceae - General characteristics - Proteus - Providencia - Morganella and extraintestinal E. coli 1 3-Bacillus - Corynebacterium and Listeria genera 1 5-Klebsiella - Enterobacter - Citrobacter - Serratia - Yersinia species 1 6- Pseudomonas - Burkholderia - Stenotrophomonas and Acinetobacter genera 1 8-Anaerobic spore-free bacteria 1 7-Haemophilus - Bordetella and Pasteurella genera 1 10-Borrelia - Leptospira and Spirillum genera 1 11-Rickettsia - Orientia and Coxiella genera 1 12-Candida genus and other yeasts of clinical importance 1 9-Clostridium genus 1 13-Zygomycetes and dematoid fungi 1 14-Malassezia - Hortea - Piedraia - Trichosporon - Microsporum - Trichophyton - Epidermophyton genera 1 15-Rubella and mumps viruses 1 16-Measles and chickenpox viruses 1 17-Herpesviruses (HSV-1 2 - HHV-6 7 8) and adenoviruses 1 18-Viral hepatitis factors (A and E) 1 19-Viral hepatitis factors (B (D and C) 1 20-HIV and other retroviruses 1 21-Prions and microorganism-prion differences 1 22-Oncogenic viruses and microorganism-cancer relationship 1 23-Vaccines 1 24-Surveillance and control of microorganisms 1 Epidemiology of hospital infections 1
23) Medical Pathology 1-Introduction to Pathology 1 2-Cell development, maturation and differentiation 1 3-Causes of cell damage and cell death 1 4-Necrosis somatic death apoptosis 1 5-Cellular adaptation and intracellular accumulations 1 6-Amyloidosis 1 7-Inflammation I-Definition - naming - pathogenesis of acute inflammation 1 8-Inflammation II-Chemical mediators and chronic inflammation 1 9-Inflammation III-Morphology of inflammation, healing and live disease factors 1 10-Neoplasia-Definition - terminology - classification - general morphological features of benign and malignant tumors 1 11-Cancer epidemiology - clinical and pathological staging prognosis 1 12-Carcinogenesis I-Oncogenes 1 13-Carcinogenesis II-Carcinogenic agents 1 14-Tumor biology-Cell kinetics - Spread and metastasis 1 15-Edema and shock 1 16-Thrombus - embolus - infarction 1 17-Molecular pathology and genetics 1
23) Medical Pathology 1-Introduction to Pathology 1 2-Cell development, maturation and differentiation 1 3-Causes of cell damage and cell death 1 4-Necrosis somatic death apoptosis 1 5-Cellular adaptation and intracellular accumulations 1 6-Amyloidosis 1 7-Inflammation I-Definition - naming - pathogenesis of acute inflammation 1 8-Inflammation II-Chemical mediators and chronic inflammation 1 9-Inflammation III-Morphology of inflammation, healing and live disease factors 1 10-Neoplasia-Definition - terminology - classification - general morphological features of benign and malignant tumors 1 11-Cancer epidemiology - clinical and pathological staging prognosis 1 12-Carcinogenesis I-Oncogenes 1 13-Carcinogenesis II-Carcinogenic agents 1 14-Tumor biology-Cell kinetics - Spread and metastasis 1 15-Edema and shock 1 16-Thrombus - embolus - infarction 1 17-Molecular pathology and genetics 1
24) Medical Pharmacology Introduction to pharmacology 1 Drug development and clinical trials 1 Translational research 1 Forms and routes of administration of drugs 1 Pharmacokinetics - Absorption of drugs 1 Pharmacokinetics - Distribution of drugs and binding to proteins 1 Pharmacokinetics - Biotransformation processes of drugs 1 Pharmacokinetics - Elimination of drugs 1 Mechanisms of action of drugs - Dose-concentration-effect interactions I 1 Mechanisms of action of drugs - Dose-concentration-effect interactions II 1 Receptors/receptor-drug interactions 1 Factors that modify the effects of drugs. Interactions between drugs 1 Pharmacogenetics 1 Pharmacovigilance 1
25) INTERNAL DISEASES 1-Why does the kidney get sick? 1 2-Fluid-electrolyte balance disorders Case examples 1 3-Evaluation of laboratory examinations used in urinary system examination 1 4-Acid-base balance disorders - Case examples 1 4-Overview of Adult Endocrinology with cases 1 PEDIATRICS 10-Overview of Pediatric Endocrinology with cases 1 UROLOGY 1-Urinary system examination methods 1 RADIODIAGNOSTICS 1-Endocrine system head and neck radiology I 1 1-Endocrine system head and neck radiology II 1 3-Endocrine system: abdominal and other system radiology 1 MEDICAL GENETICS 1-Developmental genetics (signaling pathways - transcription factors) 1 PUBLIC HEALTH 1-Environmental Endocrine Disruptors and Screening Programs 1
26) PUBLIC HEALTH 1-Food Safety-Basic Principles in Public Nutrition 1 INTERNAL DISEASES 1-Dyspeptic Patient 1 2-Gastrointestinal system case examples 1-Diabetes epidemiology 2-Diabetes mellitus preclinical and clinical period diagnostic criteria and classification 3-Case report: Diabetes mellitus 1 PEDIATRICS 4-Healthy eating principles 1 5-Nutrition of children and young people / Prof.Dr. Gülden GÖKÇAY (Dr. Lecturer Meryem KARACA) 1 6-Overview of history and findings in inherited metabolic diseases 1 7-Case examples in inherited metabolic diseases 1 8-Hereditary Glycogen Fructose and galactose metabolism diseases case examples 1
27) PEDIATRICS Protective immune response and memory response in vaccination 1 CARDIOLOGY Overview of cardiovascular system diseases 1 ECG Case Report (Adult Cardiology) 1 Sample of Circulatory System Disorders in Adults 1 PUBLIC HEALTH 1-Epidemiology of circulatory system diseases 1 2-Prevention and Control Programs 1
28) INTERNAL DISEASES 1-Why does the kidney get sick? 1 2-Fluid-electrolyte balance disorders Case examples 1 3-Evaluation of laboratory examinations used in urinary system examination 1 4-Acid-base balance disorders - Case examples 1 4-Overview of Adult Endocrinology with cases 1 PEDIATRICS 10-Overview of Pediatric Endocrinology with cases 1 UROLOGY 1-Urinary system examination methods 1 RADIODIAGNOSTICS 1-Endocrine system head and neck radiology I 1 1-Endocrine system head and neck radiology II 1 3-Endocrine system: abdominal and other system radiology 1 MEDICAL GENETICS 1-Developmental genetics (signaling pathways - transcription factors) 1 PUBLIC HEALTH 1-Environmental Endocrine Disruptors and Screening Programs 1

Sources

Course Notes / Textbooks: - Hall J, Hall M. Guyton and Hall Textbook of Medical Physiology, 14th ed (Guyton Physiology). Elseiver, 2020 .
- Glantz, Stanton “A Primer of Biostatistics” McGrow-Hill , NewYork,
2002
- Armitage, P., “ Statistical Methods in Medical Research” Blackwell
Science, Oxford,2002
- B. G. Katzung: Basic and Clinical Pharmacology, 12th ed. McGraw-Hill
Companies, New York, 2012.
- Goodman&Gilman’s The Pharmacologic Basis of Therapeutics, 12th
ed.McGraw Hill Medical, 2011
-MURRAY, P. R.; ROSENTHAL, K. S.; PFALLER,
References: - Hall J, Hall M. Guyton and Hall Textbook of Medical Physiology, 14th ed (Guyton Physiology). Elseiver, 2020 .
- Glantz, Stanton “A Primer of Biostatistics” McGrow-Hill , NewYork,
2002
- Armitage, P., “ Statistical Methods in Medical Research” Blackwell
Science, Oxford,2002
- B. G. Katzung: Basic and Clinical Pharmacology, 12th ed. McGraw-Hill
Companies, New York, 2012.
- Goodman&Gilman’s The Pharmacologic Basis of Therapeutics, 12th
ed.McGraw Hill Medical, 2011
-MURRAY, P. R.; ROSENTHAL, K. S.; PFALLER,

Course - Learning Outcome Relationship

No Effect 1 Lowest 2 Medium 3 Highest
       
Program Outcomes Level of Contribution
1) Has the ability to evaluate the source, boundaries, accuracy, reliability, and validity of knowledge and skills related to the health field.
2) Integrates knowledge, skills, and attitudes learned from basic, internal, and surgical medical disciplines in the field of health within an ethical framework.
3) Carries out the duties of a physician with a fair approach, considering ethical values without discrimination based on language, religion, race, or sexual orientation.
4) Manages general health problems related to all stages of life within the scope of primary care medicine.
5) Interprets scientific data under evidence-based medical principles, based on the knowledge acquired in the field of health.
6) Demonstrates a trustable and rational approach to providing health services, prioritizing patient and employee health, and collaborating with the community.
7) Executes health services based on evidence and up-to-date medical information, considering the patient’s conditions and needs.
8) Monitors and evaluates current events related to health at the national and global levels.
9) Applies the knowledge and skills acquired most appropriately to improve patient health and combat diseases.
10) Strives to provide the most current and high-quality health services, learns from mistakes with insight, self-evaluates, and remains open to criticism in pursuit of excellence.
11) Provides the best care for patients and their families by acting sensitively to their well-being.
12) Behaves under professional standards in a fair, honest, and respectful manner in professional relationships with patients and colleagues.
13) Respect patients’ values and privacy rights, adhering to professional confidentiality in the physician-patient relationship.
14) Ensures the protection and improvement of health services by conducting education and activities related to individual and community health within a team framework, without forgetting that access to health is a fundamental right.
15) Share thoughts on topics related to the field, as well as possible solutions to problems, with colleagues within a team, supported by scientific data.
16) Communicates effectively with patients, their families, individuals with special needs, colleagues, other healthcare workers, and institutions.
17) As a healthcare provider, take responsibility for self-improvement and maintain competence, prioritizing personal well-being.
18) Contributes to the production and development of scientific knowledge based on professional needs.
19) Contributes significantly to evidence-based medicine and One Health areas nationally and internationally through scientific research conducted under universal ethical rules.
20) Embraces the concept of lifelong learning by making behavioral changes to access up-to-date information in the field.

Learning Activity and Teaching Methods

Alan Çalışması
Akran Değerlendirmesi
Anlatım
Beyin fırtınası /Altı şapka
Bireysel çalışma ve ödevi
Course
Grup çalışması ve ödevi
Labs
Okuma
Homework
Problem Çözme
Proje Hazırlama
Rapor Yazma
Rol oynama
Seminar
Soru cevap/ Tartışma
Sosyal Faaliyet
Teknik gezi
Uygulama (Modelleme, Tasarım, Maket, Simülasyon, Deney vs.)
Örnek olay çalışması
Web Tabanlı Öğrenme
Staj/Yerinde Uygulama

Measurement and Evaluation Methods and Criteria

Assessment & Grading

Semester Requirements Number of Activities Level of Contribution
total %
PERCENTAGE OF SEMESTER WORK % 0
PERCENTAGE OF FINAL WORK %
total %

İş Yükü ve AKTS Kredisi Hesaplaması

Activities Number of Activities Aktiviteye Hazırlık Aktivitede Harçanan Süre Aktivite Gereksinimi İçin Süre Workload
Course Hours 14 451 6314
Laboratory 14 73 1022
Application 10 73 730
Special Course Internship (Work Placement) 10 73 730
Study Hours Out of Class 14 150 2100
Midterms 6 12 72
Final 1 2 2
Total Workload 10970