Medicine (English) Preview
Bachelor	TR-NQF-HE: Level 7	QF-EHEA: Second Cycle	EQF-LLL: Level 7

Course General Introduction Information

Course Code:

MED025

Course Name:

Stem Cells and Regenerative Medicine

Course Semester:

Fall

Course Credits:

ECTS

Language of instruction:

Course Requirement:

Does the Course Require Work Experience?:

Type of course:

University Ellective

Course Level:

Bachelor

TR-NQF-HE:7. Master`s Degree

QF-EHEA:Second Cycle

EQF-LLL:7. Master`s Degree

Mode of Delivery:

E-Learning

Course Coordinator :

Dr.Öğr.Üyesi TAYFUN DİKMEN

Course Lecturer(s):

Dr. Öğr. Üyesi Tayfun Dikmen

Course Assistants:

Course Purpose and Content

Course Objectives:

The aim of the course is to provide medical students with knowledge in the field of stem cell and regenerative medicine; to learn about innovative treatment approaches in stem cell application, bioengineering, cellular therapy methods and medical innovations obtained from current research.

Course Content:

1-History of Stem Cells, Important Inventions and Stem Cells Research in Our Country
2-Classification of Stem Cells, Adult Stem Cells
3-Cell Culture Equipment and Materials
4-Primary Cell Isolation and Charachterization
5-Mesenchymal Stem Cells, Induced Pluripotent Stem Cells and Embryonic Stem Cells
6-Differentiation Mechanisms of Mesenchymal Stem Cells, Action Mechanism and Paracrine Effects of Stem Cells
7-Medicine Approaches and Ethics, Platelet Rich Plasma (PRP), Stromal Vascular Fraction (SVF) and Their Clinical Potentials
8-Conditioned Medium and Its Clinical Potential, Exosomes and Their Clinical Potantial
9-Clinical Potential of Stem Cells
10-Tissue Engineering - Choosing the Biomaterial, Choosing the Stem Cell Source and Designing of the Study
11-Muscoskeletal Tissue Engineering, Neural Tissue Engineering
12-Cancer Stem Cells; Use of Cell Culture and Stem Cells in anti-Cancer Research, Drug Targeted Theraphy Systems
13-Group Study: Preparation of an Exemplary Study
14- Group Study: Preparation of an Exemplary Study

Learning Outcomes

The students who have succeeded in this course;
1) Students taking the course know stem cells, cellular therapy methods, tissue engineering approaches used in the field of regenerative medicine. They can use this knowledge competently in preparing a research project and following the articles published in the field. Students will be able to know the general properties of stem cells, isolation and characterisation methods, and their potential use in therapy.

Course Flow Plan

Week	Subject	Related Preparation
1)
2)
3)
4)
5)
6)
7)
8)
9)
10)
11)
12)
13)		Repetition of previous courses
14)		Repetition of previous courses. Group work must be submitted before the class

Sources

Course Notes / Textbooks:

References:

1-TÜBA- Kök Hücre Araştırmalarında Güncel Kavramlar, 2004, ISBN: 975-8593-63-3
2-Kök Hücre, Prof. Dr. Alp Can, ISBN: 9786257409629
3-Culture of Animal Cells: A Manual of Basic Technique and Specialized Applications, R. Ian Freshney, ISBN: 9780470649367
4-TÜBA- Kök Hücre Biyolojisi ve Klinik Uygulamalar, ISBN: 978-9944-252-29-4
5-Biomaterials and Tissue Engineering, Oguzhan Gunduz, ISBN 978-3-031-35831-9
6-Novel Biomaterials for Regenerative Medicine, Heung Jae Chun, ISBN 978-981-13-0946-5
7-KONTROLLÜ SALIM SİSTEMLERİ, Aylâ Z. Gürsoy
8-Cancer Stem Cells, Liu and Justin D. Lathia, ISBN 978-0-12-803892-5

Course - Learning Outcome Relationship

No Effect	1 Lowest	2 Medium	3 Highest

	Program Outcomes	Level of Contribution
1)	Has the ability to evaluate the source, boundaries, accuracy, reliability, and validity of knowledge and skills related to the health field.
2)	Integrates knowledge, skills, and attitudes learned from basic, internal, and surgical medical disciplines in the field of health within an ethical framework.
3)	Carries out the duties of a physician with a fair approach, considering ethical values without discrimination based on language, religion, race, or sexual orientation.
4)	Manages general health problems related to all stages of life within the scope of primary care medicine.
5)	Interprets scientific data under evidence-based medical principles, based on the knowledge acquired in the field of health.
6)	Demonstrates a trustable and rational approach to providing health services, prioritizing patient and employee health, and collaborating with the community.
7)	Executes health services based on evidence and up-to-date medical information, considering the patient’s conditions and needs.
8)	Monitors and evaluates current events related to health at the national and global levels.
9)	Applies the knowledge and skills acquired most appropriately to improve patient health and combat diseases.
10)	Strives to provide the most current and high-quality health services, learns from mistakes with insight, self-evaluates, and remains open to criticism in pursuit of excellence.
11)	Provides the best care for patients and their families by acting sensitively to their well-being.
12)	Behaves under professional standards in a fair, honest, and respectful manner in professional relationships with patients and colleagues.
13)	Respect patients’ values and privacy rights, adhering to professional confidentiality in the physician-patient relationship.
14)	Ensures the protection and improvement of health services by conducting education and activities related to individual and community health within a team framework, without forgetting that access to health is a fundamental right.
15)	Share thoughts on topics related to the field, as well as possible solutions to problems, with colleagues within a team, supported by scientific data.
16)	Communicates effectively with patients, their families, individuals with special needs, colleagues, other healthcare workers, and institutions.
17)	As a healthcare provider, take responsibility for self-improvement and maintain competence, prioritizing personal well-being.
18)	Contributes to the production and development of scientific knowledge based on professional needs.
19)	Contributes significantly to evidence-based medicine and One Health areas nationally and internationally through scientific research conducted under universal ethical rules.
20)	Embraces the concept of lifelong learning by making behavioral changes to access up-to-date information in the field.

Learning Activity and Teaching Methods

Anlatım
Beyin fırtınası /Altı şapka
Course
Grup çalışması ve ödevi

Measurement and Evaluation Methods and Criteria

Yazılı Sınav (Açık uçlu sorular, çoktan seçmeli, doğru yanlış, eşleştirme, boşluk doldurma, sıralama)
Grup Projesi

Assessment & Grading

Semester Requirements	Number of Activities	Level of Contribution
Presentation	1	% 10
Midterms	1	% 40
Final	1	% 50
total		% 100
PERCENTAGE OF SEMESTER WORK		% 50
PERCENTAGE OF FINAL WORK		% 50
total		% 100

İş Yükü ve AKTS Kredisi Hesaplaması

Activities	Number of Activities	Aktiviteye Hazırlık	Aktivitede Harçanan Süre	Aktivite Gereksinimi İçin Süre	Workload
Course Hours	14	2			28
Study Hours Out of Class	14	1			14
Presentations / Seminar	1	1			1
Midterms	1	1			1
Final	1	1			1
Total Workload					45