Istanbul Health and Technology University INFORMATION PACKAGE / COURSE CATALOGUE
| Medicine (English) | |||||
| Bachelor | TR-NQF-HE: Level 7 | QF-EHEA: Second Cycle | EQF-LLL: Level 7 | ||
Course General Introduction Information
| Course Code: | MED100.03 | ||||
| Course Name: | Normal Structure and Function Committee -I | ||||
| Course Semester: | Fall | ||||
| Course Credits: |
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| Language of instruction: | EN | ||||
| Course Requirement: | |||||
| Does the Course Require Work Experience?: | No | ||||
| Type of course: | Necessary | ||||
| Course Level: |
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| Mode of Delivery: | |||||
| Course Coordinator : | Öğr.Gör. GKİONOUL NTELİ CHATZIOGLOU | ||||
| Course Lecturer(s): | Sema Genç; Ozan Toraman; Gkionoul Nteli Chatzioglou; Esmanur Okutan; Dilek Akakın; Gülden Budak; Feriha Ercan | ||||
| Course Assistants: |
Course Purpose and Content
| Course Objectives: | |
| Course Content: |
Learning Outcomes
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The students who have succeeded in this course;
1) Medical Biochemistry: the course covers a wide array of learning outcomes essential for understanding the biochemical basis of life processes. Students delve into the definition and biological significance of proteins, encompassing both standard and non-standard amino acids, along with their functions and chemical properties including peptide bond formation. The course elaborates on protein structure, discussing fibrillar proteins like collagen and keratin, as well as globular proteins such as hemoglobin and myoglobin. Additionally, students explore the general characteristics and classification of enzymes, factors influencing enzyme activity, enzyme inhibition, and the regulation of enzyme activity. The curriculum also addresses vitamins, their classification into fat-soluble and water-soluble types, and their roles in metabolic pathways, providing a comprehensive understanding of biochemical principles underlying physiological processes. 2) Biophysics: the course begins with an introduction to bioenergetics, including concepts and terminology, along with thermodynamic laws. Biological energy transfer, free energy, and entropy are also examined within this framework. Subsequently, the molecular basis of biological reactions and enzyme action mechanisms, such as enzyme kinetics, are explored. The physical principles of enzymes and the regulation of enzyme activity elucidate the control mechanisms of intracellular reactions. The development of the cell cycle and regulators of cyclins, as well as molecular mechanisms determining cell differentiation and specificity, are also significant topics. The biophysical energetics of aging, molecular biophysical methods, medical applications of nanobiotechnology, and new approaches to cancer issues are advanced subjects included in the course. These learning outcomes aim to equip students with the skills to comprehend the physical aspects of biological systems and develop innovative solutions in medical applications. 3) Medical Biology: encompasses various essential learning outcomes related to cellular processes, genetics, and heredity. Beginning with mitosis and the cell cycle, students delve into the intricacies of cell division and its regulation. Understanding the mechanisms underlying chromosome movements during mitosis is crucial, alongside exploring meiosis and chromosomal irregularities that occur during this process. The principles of Mendelian genetics and inheritance patterns elucidate how traits are passed from one generation to another. Moreover, non-Mendelian inheritance mechanisms are also examined to understand genetic complexities beyond Mendel's laws. The role of gonosomal chromosomes, such as X chromosome inactivation, sheds light on sex-linked inheritance patterns. Autosomal dominant and recessive inheritance, as well as X-linked dominant and recessive inheritance, further expand students' comprehension of genetic inheritance. Additionally, the characteristics and significance of stem cells are explored, emphasizing their regenerative potential and role in tissue repair. These learning outcomes provide students with a comprehensive understanding of fundamental biological processes and genetic principles underlying human health and inheritance patterns. 4) Physiology: It examines the complex mechanisms underlying the functioning of the human body. Students gain an understanding of the concept of homeostasis, which is crucial for maintaining stability in the body's internal environment. The course explores the various control systems of the body that regulate physiological processes to ensure homeostasis. Additionally, students investigate biological rhythms, which are inherent cycles dictating various physiological functions. Understanding the regulation and maintenance of acid-base balance in body fluids is essential, as it directly impacts cellular function. Osmosis and transport mechanisms are examined in detail, elucidating how substances are transported across cell membranes to maintain homeostasis. Furthermore, the course covers the compartments of body fluids and their ion compositions, providing insights into the distribution and regulation of essential electrolytes within the body. These learning outcomes equip students with a comprehensive understanding of the physiological processes that govern human health and function. 5) Histology and Embryology: the course of Histology and Embryology provides students with an in-depth understanding of tissue development and embryogenesis. By examining the development and structure of epithelial tissue, students learn how these tissue types form and what their structures entail. Various types of epithelial tissues, such as surface epithelium and glandular epithelium, are extensively explored, along with the characteristics and functions of sensory epithelium. Focusing on the development of connective tissue, the course provides information about connective tissue fibers and matrix. Understanding connective tissue cells offers students a comprehensive insight into the structural and functional properties of this tissue. These learning outcomes provide students with a solid foundation to comprehend the complex structures of tissues and embryonic development, aiding in understanding their functions effectively. 6) Medical Microbiology: The course aims to equip students with comprehensive knowledge regarding various aspects of immunity and immunological responses. It begins by exploring natural immunity mechanisms, providing insights into the body's innate defense mechanisms against pathogens. Students delve into the concept of antigens, their processing, and presentation to lymphocytes, crucial for understanding the initiation of immune responses. Acquired immunity mechanisms are extensively covered, focusing on the recognition of antigens in acquired immunity and the role of lymphocytes in mounting immune responses. Cellular immunity and humoral immunity, mediated by cells and antibodies respectively, are examined in detail, elucidating their roles in combating infections. Additionally, the course delves into topics such as autoimmunity and tolerance, shedding light on the mechanisms underlying immune tolerance and the breakdown of self-tolerance leading to autoimmune diseases. Hypersensitivity reactions and immunodeficiency disorders are also discussed, providing insights into abnormal immune responses and their consequences. Furthermore, the course addresses tumor immunology and transplant immunology, exploring immune responses against tumors and the immunological basis of transplant rejection. These learning outcomes aim to provide students with a comprehensive understanding of the immune system's functions, dysfunctions, and its role in health and disease. 7) Anatomy: The course aims to comprehensively teach students about the structure of the human body. The course begins with an introduction to anatomy, providing an understanding of basic anatomical terms and concepts. Movement anatomy examines the attachment of muscles to the skeletal system and their ability to move. Students learn about major bones such as the os coxae and femur. Lower extremity bones like the tibia, fibula, patella, and ossa pedis are detailed, as well as upper extremity bones like the clavicle, scapula, and humerus. Bones of the arm, including the radius, ulna, and ossa manus, are studied to understand arm anatomy. The structure and function of spine bones are covered under the columna vertebralis, while body bones like ossa thoracis and pelvis are examined. Skull bones and facial bones provide insight into the structural features of the skull and face. The concept of the head as a whole encompasses the overall anatomy of the skull and face, aiding students in understanding the holistic structure of the human body. These learning outcomes provide students with a comprehensive understanding of the anatomical structure and functions of the human body, laying the foundation for advancements in medicine and health sciences. |
Course Flow Plan
| Week | Subject | Related Preparation |
| 1) | Anatomy: - Introduct*on to anatomy - Anatomy of locomotor system - Os coxae – femur - Tibia, fibula, patella, bones of foot (ossa pedis) Medical Biochemistry: - Definition and biological significance of proteins - Standard and nonstandard amino acids Physiology: - Concept of homeostasis in the human body | Course Presentation |
| 1) | Anatomy: - Introduct*on to anatomy - Anatomy of locomotor system - Os coxae – femur - Tibia, fibula, patella, bones of foot (ossa pedis) Medical Biochemistry: - Definition and biological significance of proteins - Standard and nonstandard amino acids Physiology: - Concept of homeostasis in the human body | Course Presentation |
| 1) | Medical Biochemistry: Biochemistry of connective and bone tissue; Muscle biochemistry, Biophysics: Molecular mechanism of mechanical work (muscle contraction); Adaptation of the cell to changes in environmental conditions or response to a stimulus; Modifications beyond synthesis, Medical Biology: Gene and genome structure; Gene mutations; Mutagenic factors and mutation detection methods, Anatomy: Joint general information; Head and trunk joints, Physiology: Peripheral nerve physiology; Muscle physiology - classification of muscles - general structure of muscle fibers, Histology and Embryology: Muscle tissue - skeletal muscle; Cardiac muscle; Smooth muscle, Public Health: Basic characteristics of health services and health policies; Provision of health services in Turkey and in the world - health manpower | Course presentation |
| 2) | Anatomy: - Clavicula, scapula, humerus - Radius, ulna, bones of hand (ossa manus) Biophysics: -Introduction to bioenergetics - concepts and terms - thermodynamic rules Medical Biochemistry: - Functions of amino acids - Chemical properties of amino acids, peptide bond formation - Protein structure Histology and Embryology: - Development and structure of Epithelial Tissue - Types of Epithelial Tissues - Surface Epithelium and Glandular Epithelium - Sensory Epithelium Physiology: - Control systems of the body Medical Biology: - Mitosis and cell cycle - Regulation of the cell cycle | Course Presentation |
| 3) | Anatomy: - Vertebral column, Bones of thorax (Ossa thoracis), bones of pelvis Medical Biology: - Mechanisms of chromosome movements in mitosis, Meiosis and Chromosome Irregularities Physiology: - Biological rhythms Medical Biochemistry: Protein structure, Fibrillar proteins, collagen and keratin, Globular Proteins,Hemoglobins And Miyoglobins Histology and Embryology: - Development of connective tissue, Connective tissue fibers and matrix, Cells of connective tissue Biophysics: - Biological energy transfer - concept of free energy and entropy, Molecular basis of biological reactions and enzyme action mechanism enzyme kinetics Enzymes- physical principles - regulation of enzyme activity | Course Presentation |
| 4) | Anatomy: Cranial bones; Biophyscis: Regulators of cell cycle development and cyclins Immunobiophysics; Lymphocyte model in terms of cell differentiation; Molecular mechanisms that determine the specificity of cell differentiation; Molecular principles of cell development and differentiation; Physiology: Regulation and maintenance of acid-base balance in body fluids Medical Biology: Mendelian Genetics and inheritance; non-mendelian inheritance; Gonosomal chromosomes – X chromosome inactivation; Autosomal dominant and recessive inheritance, Medical Biochemistry: General properties and classification of enzymes; Factors affecting enzyme activity | Course presentation |
| 5) | Anatomy: Facial bones, Biophysics: Molecular principles of cell development and differentiation; Bioenergetics of aging, Physiology: Osmosis and transport, Medical Biochemistry: Enzyme inhibition; Regulation of enzyme activity | Course presentation |
| 6) | Anatomy: Gross Anatomy of Cranium; Normas, Medical Biochemistry: Vitamins, their classification; Fat-soluble vitamins, Biophysics: Nanobiotechnology medical applications; New approaches to the cancer problem | Course presentation |
| 7) | Medical Biology: X-linked dominant and recessive inheritance; Stem cells and their properties, Physiology: Body fluid compartments and ion compositions Medical Biochemistry: Fat-soluble vitamins; Water soluble vitamins, Laboratory courses | Course presentation |
| 8) | Exam | Course presentation |
Sources
| Course Notes / Textbooks: | |
| References: |
Course - Learning Outcome Relationship
| No Effect | 1 Lowest | 2 Medium | 3 Highest |
| Program Outcomes | Level of Contribution | |
| 1) | Has the ability to evaluate the source, boundaries, accuracy, reliability, and validity of knowledge and skills related to the health field. | |
| 2) | Integrates knowledge, skills, and attitudes learned from basic, internal, and surgical medical disciplines in the field of health within an ethical framework. | |
| 3) | Carries out the duties of a physician with a fair approach, considering ethical values without discrimination based on language, religion, race, or sexual orientation. | |
| 4) | Manages general health problems related to all stages of life within the scope of primary care medicine. | |
| 5) | Interprets scientific data under evidence-based medical principles, based on the knowledge acquired in the field of health. | |
| 6) | Demonstrates a trustable and rational approach to providing health services, prioritizing patient and employee health, and collaborating with the community. | |
| 7) | Executes health services based on evidence and up-to-date medical information, considering the patient’s conditions and needs. | |
| 8) | Monitors and evaluates current events related to health at the national and global levels. | |
| 9) | Applies the knowledge and skills acquired most appropriately to improve patient health and combat diseases. | |
| 10) | Strives to provide the most current and high-quality health services, learns from mistakes with insight, self-evaluates, and remains open to criticism in pursuit of excellence. | |
| 11) | Provides the best care for patients and their families by acting sensitively to their well-being. | |
| 12) | Behaves under professional standards in a fair, honest, and respectful manner in professional relationships with patients and colleagues. | |
| 13) | Respect patients’ values and privacy rights, adhering to professional confidentiality in the physician-patient relationship. | |
| 14) | Ensures the protection and improvement of health services by conducting education and activities related to individual and community health within a team framework, without forgetting that access to health is a fundamental right. | |
| 15) | Share thoughts on topics related to the field, as well as possible solutions to problems, with colleagues within a team, supported by scientific data. | |
| 16) | Communicates effectively with patients, their families, individuals with special needs, colleagues, other healthcare workers, and institutions. | |
| 17) | As a healthcare provider, take responsibility for self-improvement and maintain competence, prioritizing personal well-being. | |
| 18) | Contributes to the production and development of scientific knowledge based on professional needs. | |
| 19) | Contributes significantly to evidence-based medicine and One Health areas nationally and internationally through scientific research conducted under universal ethical rules. | |
| 20) | Embraces the concept of lifelong learning by making behavioral changes to access up-to-date information in the field. |
Learning Activity and Teaching Methods
| Anlatım | |
| Labs | |
| Uygulama (Modelleme, Tasarım, Maket, Simülasyon, Deney vs.) |
Measurement and Evaluation Methods and Criteria
| Yazılı Sınav (Açık uçlu sorular, çoktan seçmeli, doğru yanlış, eşleştirme, boşluk doldurma, sıralama) | |
| Uygulama |
Assessment & Grading
| Semester Requirements | Number of Activities | Level of Contribution |
| total | % | |
| PERCENTAGE OF SEMESTER WORK | % 0 | |
| PERCENTAGE OF FINAL WORK | % | |
| total | % | |
İş Yükü ve AKTS Kredisi Hesaplaması
| Activities | Number of Activities | Aktiviteye Hazırlık | Aktivitede Harçanan Süre | Aktivite Gereksinimi İçin Süre | Workload | ||
| Course Hours | 5 | 65 | 325 | ||||
| Total Workload | 325 | ||||||